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无梗五加果实抗疲劳活性研究 被引量:10

Study on the Anti-fatigue Effect of Acanthopanax Sessiliflorus Fruits
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摘要 目的:研究无梗五加果实各提取物的抗疲劳作用,为无梗五加的广泛应用提供依据。方法:采用小鼠力竭游泳实验,考察连续灌胃无梗五加果实提取物2周对小鼠抗疲劳能力的影响,并对给药后小鼠体内血乳酸、血尿素氮、肝糖原和肌糖原的变化进行检测。结果:无梗五加果实提取物能够延长小鼠力竭游泳时间、降低小鼠运动后的乳酸堆积和血尿氮的生成,增加肝糖原、肌糖原的储备量。结论:无梗五加果实具有抗疲劳作用,尤以无梗五加果实醇提物抗疲劳作用最显著。 Objective:To study on the anti-fatigue effect of the extract of Acanthopanax sessiliflorus fruits,to provide the basis for the wide application of Acanthopanax sessiliflorus. Methods : Exhaustive swimming test were employed to evaluate anti-fatigue effect of extracts of Acanthopanax sessiliflorus fruits in mice, extract orally administraded for two weekends consecutively. Further, lactic acid level and urea nitrogen level were examined,and hepatic gly-Cogen and muscle glycogen level after swimming were determined. Results:The extract of Acanthopanax sessiliflorus fruits extended swimming time,lactic acid level and urea nitrogen level were de- crease-d, hepatic glycogen and muscle glycogen level were increased after Treatment. Conclusion: Acanthopanax sessiliflorus fruits have obvious anti-fatigue effects, the alcohol extract the of Acanthopanax sessiliflorus fruits showed more remarkable anti- fatigue.
出处 《亚太传统医药》 2015年第19期10-12,共3页 Asia-Pacific Traditional Medicine
关键词 抗疲劳 无梗五加果实 血乳酸 血尿素氮 肝糖原 肌糖原 Anti-fatigue Acanthopanax Sessiliflorus Fruits~ Blood Lactic Acid~ Blood Urea Nitrogen Hepatic Glycogen MuscleGlycogen
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