摘要
急性肾损伤（ acute kidney injury,AKI）是指各种原因导致的肾功能的快速受损,引起肾小球滤过率下降,血清尿素氮升高,血清肌酐升高,尿量减少,从而导致人体内环境紊乱,机体不能维持稳态,增加了新生儿的病死率和患慢性肾病的危险。了解AKI的诊断标准、病因及发病机制、早期生物标记物、治疗及预后的有关研究进展,对指导临床早期诊治新生儿AKI,改善新生儿AKI预后,降低患儿病死率极为重要。
Acute kidney injury（ AKI） is a variety of causes leading to rapid impaired renal function, causing glomerular filtration rate reduced,blood urea nitrogen elevated,serum creatinine increased,urine out-put decreased,resulting in the disorder of the human body environment,so the body can not maintain homeo-stasis. AKI increases the risk of mortality and chronic kidney disease in neonate. To understand the progress of AKI on diagnostic criteria,pathogenesis,early biomarker,treatment and prognosis,it is extremely important to guide clinical diagnosis and treatment,improve the outcome and reduce the mortality of AKI in neonate.
出处
《中国小儿急救医学》
CAS
2015年第9期624-628,共5页
Chinese Pediatric Emergency Medicine
