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NGAL的结构与功能及其在肾脏疾病中的作用 被引量:2

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摘要 NGAL是一种新发现的lipocalin,存在于人体内许多正常组织细胞中,可能与免疫炎症反应、肿瘤的发生发展以及肾脏疾病有关。现就NGAL的结构、功能及其与肾脏疾病的相关性进行综述。
出处 《国际移植与血液净化杂志》 2007年第3期7-9,共3页 International Journal of Transplantation and Hemopurification
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  • 1张建国,丁涵露,任姜汶,高闻达.慢性间质性肾炎中NGAL的表达及其作用的研究[J].西部医学,2006,18(6):691-693. 被引量:8
  • 2Bolignano D, Donato V, Coppolino G, et al. Neutrophil gelatinase- associated lipocalin(NGAL) as a marker of kidney damage[ J]. Am J Kidney Dis,2008,52(3) :595-605. 被引量:1
  • 3Devarajan P. Neutrophil gelatinase-associated lipocalin (NGAL) :a new marker of kidney disease[ J]. Scand J Clin Lab Invest Suppl, 2008,241:89-94. 被引量:1
  • 4Bundgaard JR, Sengelov H, Borregaard N, et al. Molecular cloning and expression of a eDNA encoding NGAL:a lipocalin expressed in human neutrophils[J].J bioehem Biophys Res Commun, 1994, 202 (3) : 1468-1475. 被引量:1
  • 5Kjeldsen L, Cowland JB, Borregaard N. Human neutrophi 1 gelatinase associated lipocalin and homologous proteins in rat and mouse[J]. J Biochim Biophys Acta,2000,1482 ( 122 ) :272-283. 被引量:1
  • 6Bolignano D, Donato V, Lacquaniti A. Neutrophil gelatinase-associated lipocalin (NGAL) in human neoplasias : A new protein enters the scene [ J ]. Cancer Lett,2009. 被引量:1
  • 7Zhang XF, Zhang Y, Zhang XH. Clinical significance of neutrophil gelatinase-associated lipocalin(NGAL) expression in primary rectal cancer [ J ]. BMC Cancer,2009,6 ( 9 ) : 134. 被引量:1
  • 8Hu L, Hittelman W, Lu T,et al. NGAL decreases E-cadherin-mediated cell-cell adhesion and increases cell motility and invasion through Racl in colon carcinoma cells[J]. Lab Invest,2009,89 (5) :531-548. 被引量:1
  • 9Yang J, Goetz D, Li JY,et al. An iron delivery pathway mediated by a lipocalin[ J]. Mol Cell,2002,10(5) :1045-1056. 被引量:1
  • 10Gwira JA, Wei F, Ishibe S, et al. Expression of neutrophil gelatinase-associated lipocalin regulates epithelial morphogenesis in vitro [J]. J Biol Chem, 2005,280(9) :7875-7882. 被引量:1

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