摘要
目的研究临产孕妇凝血功能指标的变化情况,预防产后出血或血栓形成。方法采用Compact全自动血凝分析仪检测185例临产孕妇和100例健康非孕女性活化部分凝血活酶时间(APPT)、凝血酶原时间(PT)、国际标准化比值(INR)、凝血活酶时间(TT)、纤维蛋白原(FIB)、D-二聚体(D-Di)、纤维蛋白降解产物(FDP)、抗凝血酶Ⅲ(AT-Ⅲ)并进行分析。结果与健康非孕女性比较,临产孕妇的APTT、PT、AT-Ⅲ水平明显降低,FIB、D-Di、FDP水平明显升高,差异均有统计学意义(P<0.05)。结论对临产孕妇进行凝血功能的检测,可早期发现凝血功能的异常,对预防产妇全身微血栓的发生,减少分娩时并发症的发生和降低病死率有重要意义。
Objective To study the changes of blood coagulation indexes of parturient women and prevent the thrombolysis and blooding .Methods Using compact automatic coagulometer to detect 185 parturient women and 100 healthy women who were not pregnant ,the activated partial thromboplastin time（APTT） ,prothrombin time（PT） ,international normalized ratio（INR） ,thrombin time（TT） ,fibrinogen（FIB） ,D‐Dimer（D‐Di） ,fibrin degradation product（FDP） ,antithrombin‐Ⅲ （AT‐Ⅲ ） and analyze and study them .Results Compared with the healthy women ,parturient women were obviously with lower APTT ,PT ,AT‐Ⅲ values .But their FIB ,D‐Di and FDP concentrations were much higher and the differences were statistically significant（P〈0 .05） .Conclusion By testing the function of blood coagulation for parturient women ,the changes of the function of blood coagulation could be ob‐served before it is too late ,which is important for preventing the occurrence of disseminated intravasular coagulation and treat it in time .thus ,we can reduce the morbidity and mortality among parturient women .
出处
《国际检验医学杂志》
CAS
2015年第17期2541-2542,共2页
International Journal of Laboratory Medicine
