摘要
目的:建立淫羊藿饮片醇提生产工艺。方法:采用Box-Behnken试验设计结合效应面法对各工艺参数进行优选,HPLC色谱法和紫外可见分光光度法联合定量评价。结果:淫羊藿生产最佳提取工艺为:加入15倍量70%乙醇,提取150min。结论:Box-Behnken试验设计适合对因素的水平范围进行合理筛选,该工艺稳定,可行性强。
Objective： To establish the ethanol extraction process of epimedium pieces. Methods： The process parameters were optimized by Box-Behnken design combined with response surface methodology, and HPLC combined with UV was used in the quantita- tive evaluation. Results： The optimum extraction process of epimedium was as follows： 15-fold amount of 70% ethanol was added and the pieces were extracted for 150 rain. Conclusion： Box-Behnken design can be used to screen the reasonable level range of factors, and the optimal process is reliable and feasible.
出处
《中国药师》
CAS
2015年第9期1493-1495,共3页
China Pharmacist
基金
济南军区后勤科研计划(编号:CJN10L067)
