摘要
目的分析青年乳腺癌患者的临床病理特点。方法选取本院96例青年乳腺癌患者(青年组)和中老年乳腺癌患者(中老年组)病例资料进行回顾性分析。分析2组患者病理类型、TNM分级情况、腋窝淋巴结转移例数、脉管侵犯例数。比较2组患者ER、PR、Her-2等免疫组化染色结果。结果 2组患者的病理分型和TNM分级情况比较无显著差异(P>0.05)。青年组患者腋窝淋巴结转移例数和脉管侵犯例数均高于中老年患者(P<0.05)。青年组患者的ER、PR阳性率明显低于中老年组患者,但其Her-2和Ki-67染色阳性率明显高于中老年组患者(P<0.05)。2组患者的P53表达阳性情况比较无显著差异(P>0.05)。结论青年女性乳腺癌患者的病理类型和分期与中老年患者相似,但其侵袭性和转移能力更强,预后差。
Objective To analyze the clinical pathological features of young patients with breast cancer. Methods Clinical materials of 96 young patients with breast cancer patients （youth group） and old breast cancer patients （older group） were collected and analyzed retrospectively. Pathology types, TNM classification, the number of cases of axillary lymph node metastasis and vascular invasion of two groups were analyzed. ER, PR, Her-2 and some other immunohistoche- mica1 staining were compared as well. Results There were no significant differences in pathology types and TNM classification between two groups （P 〉0.05）. The number of axillary lymph node metastasis and vascular invasion of the youth group were significantly higher than those of the older group （P〈0.05）. The positive rates of ER and PR in the youth group were significantly lower than those of the older group, while the positive rates of Her-2 and Ki-67 were significantly higher （P〈0.05）. There were no significant difference in positive rate of P53 between two groups （P〉 0.05）. Conclusion Pathology types and TNM classification of young patients and elderly patients with breast cancer are similar, Invasion and metastasis of the youth patients are stronger, and the prognosis is poor.
出处
《实用临床医药杂志》
CAS
2015年第15期191-193,共3页
Journal of Clinical Medicine in Practice
关键词
青年
乳腺癌
病理特点
pathological characteristics
youth
breast cancer
