摘要
目的探讨脑梗死患者颈动脉粥样硬化斑块与血脂水平的关系。方法取住院脑梗死患者55例,同时取体检指标正常的成年人55例为对照组,用彩色多普勒超声检测颈总动脉、颈内动脉颅外段及分叉处的内-中膜厚度(intima-media thickness,IMT),同时进行血脂检查。结果脑梗死组甘油三酯(TG)、低密度脂蛋白(LDL)、载脂蛋白B(Apo B)均高于对照组,而高密度脂蛋白(HDL)、载脂蛋白A(Apo A)则低于对照组,差异有统计学意义(P<0.05);脑梗死组IMT明显增厚,颈动脉粥样硬化斑块检出及不稳定性斑块发生率高于对照组,差异有统计学意义(P<0.05)。结论甘油三酯、低密度脂蛋白水平异常与脑梗死颈动脉粥样硬化斑块的形成发生有很大的关联性。
Objective To investigate the relationship between carotid atherosclerotic plaque and levels of plasma-lipid after cerebral infarction patients（CI）. Methods 55 patients with cerebral infarction of our hospital in the latest two years were selected as the study objects and 55 normal adults were control group;Carotid artery was evaluated by color Doppler ultrasound in all study objects;Concentration of TC,TG,HDL,LDL,ApoA,ApoB were measured. Results The levels of TG,LDL,ApoB in CI group were significantly higher than control group,which HDL,ApoA in CI group were lower than control group（P 〈 0.05）;the rates IMT and unstable versus plaque in CI group were significantly higher than control group;the results were statistically significant（P〈0.05）. Conclusion The levels of plasma TC, LDL may concern with the development of cerebral infarction.
出处
《中国医药科学》
2015年第8期138-139,155,共3页
China Medicine And Pharmacy
关键词
脑梗死
颈动脉粥样硬化斑块
血脂
Cerebral infarction
Carotid atherosclerotic plaque
Plasma lipid
