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抗苗勒管激素测定在疾病诊断中的应用 被引量:13

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摘要 抗苗勒管激素(anti-Müllerian hormone,AMH)是转化生长因子-β(TGF-β)超家族成员,在女性仅由卵巢分泌,由窦前卵泡和小窦卵泡产生,是目前外周血中能检测到的最早的卵泡产生的物质,其主要生理功能是在性腺分化过程中抑制副中肾管(即苗勒管)发育。AMH最初表达于初级卵泡的颗粒细胞层,血清中AMH水平与发育的卵泡数成一定的比例。许多研究表明,AMH水平在自然周期各阶段均无明显波动,
出处 《实用妇产科杂志》 CAS CSCD 北大核心 2015年第8期565-567,共3页 Journal of Practical Obstetrics and Gynecology
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  • 1程丽平,郭跃贞,夏丽,周岩.多囊卵巢综合征与抗苗勒氏管激素的相关分析[J].中国优生与遗传杂志,2008,16(2):103-104. 被引量:3
  • 2Rey R, Lukas-Croisier C, Lasala C, et al. AMH/MIS: What we know already about the gene, the protein and its regu- lation[J]. Molecular & Cellular Endocrinology, 2003,211 (sl-2) :21-31. 被引量:1
  • 3Milan6s-Virelles MT, Garcia-Garcfa I, Santos-Herrera Y, et al. Adjuvant interferon gamma in patients with pul- monary atypical mycobacteriosis : A randomized,double - blind, placebo-controlled study[J]. Bmc Infectious Diseas- es,2008,8(1) : 1-13. 被引量:1
  • 4Durlinger AL, V isser JA,Themmen AP. Regulation of o- varian function) the role of AntiM llerian hormone[J]. Re- production, 2002, 124(5) : 601609. 被引量:1
  • 5Hirobe S,He WW,Lee MM,et al. Mullerian inhibiting substance messenger ribonucleic acid expression in granu- losa and Sertoli cells coincides with their mitotic activity[J]. Endocrinology, 1992,131 ( 131 ) : 854-862. 被引量:1
  • 6Christien W, Laven JSE, Bergh ARMV,et al. Anti-mtille- rian hormone expression pattern in the human ovary:Po- tential implications for initial and cyclic follicle recruit- ment[J]. Journal of Oral Pathology,2004,10(2) :77-83. 被引量:1
  • 7Baarends WM, Hoogerbrugge JW, Post M, et al. Anti- mtilerian hormone and anti-mtilerian hormone type II re- ceptor[J]. Reprod, 1995,50(5) : 1238-1243. 被引量:1
  • 8Rajpert-DeMeyts E, Jorgensen N, Graem N, et al. Expres- sion of anti-M llerian hormone during normal and patho- logical gonadal development association with differentiation of Sertoli and granulosa cells[J]. J Clin Endocrinol Metab, 1999,84 ( 10 ): 38363844. 被引量:1
  • 9Fang SL, Visser JA, Welt CK, et al. Serum anti-miillerian hormone levels in healthy females:A nomogram ranging From infancy to adulthood[J]. Journal of Clinical En- docrinology & Metabolism, 2012,97 (12) : 4650-4655. 被引量:1
  • 10Hagen CP, Lise A, Kaspar S,et al. Serum levels of anti- qiillerian hormone as a marker of ovarian function in 926 healthy females from birth to adulthood and in 172 turner yndrome patients[]l. Journal of Clinical Endocrinology &Metabolism, 2010,95 ( 11 ) : 5003-5010. 被引量:1

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