摘要
卵泡的发育过程是一个异常复杂的现象。在这个过程中,雄激素、促卵泡生成素(follicle stimulating hormone,FSH)、抗苗勒管激素(anti-Mullerian hormone,AMH)和雌二醇(estradiol,E_2)起着至关重要的作用。然而,这四种激素间的相互作用到目前为止并没有完全理解。深入理解它们之间的相互作用不仅能够补充我们现有的知识,同时也为其在辅助生殖领域中的应用提供理论依据。本文根据这四种激素在卵泡发育过程中出现的先后顺序分别阐明了非促性腺激素(gonadotropin,Gn)依赖期雄激素-FSH-AMH之间的相互作用及Gn依赖期FSHAMH-E_2之间的相互作用。
The development of follicles is an unusually complicated phenomenon. In this process, androgen, follicle stimulating hormone （FSH）, anti-Miillerian hormone （AMH） and estradiol （E2） play vital roles. However, the interactions between these four hormones have not been fully understood so far. In-depth understanding of the interactions between them not only can complement our existing knowledge, but also can provide a theoretical basis for their application in the field of assisted reproduction. Based on the order of occurrence of these four hormones in follicular development, the article explains the interactions between androgen-FSH-AMH in gonadotropin （Gn）-independent stage and the in- teractions between FSH-AMH-E2 in Gn-dependent stage.
出处
《中国现代医生》
2017年第3期157-160,164,共5页
China Modern Doctor
基金
国家自然科学基金(81571397)
