摘要
目的探讨不同严重程度社区获得性肺炎(CAP)患者预后与凝血功能的相关性。方法收集我院呼吸科2011年9月至2012年12月间收治的89例CAP患者,其中低危组47例、中高危组42例。比较2组的临床资料及血小板、凝血酶时间(TT)、凝血酶原时间(PT)、活化的部分凝血活酶时间(APTT)、纤维蛋白原(Fib)及D-二聚体(DD)等凝血指标,分析不同预后组患者的差异。结果中高危组PT、TT、DD数值分别是(16.2±1.5)s、(16.9±1.9)s及(8.1±7.4)mg/L,均显著高于低危组(11.5±1.4)s、(9.5±1.7)s及(1.6±3.2)mg/L,差异具有统计学意义(P<0.01),血小板、APTT、Fib差异无统计学意义(P>0.05)。结论 CAP可导致凝血功能紊乱,患者血中的DD随病情严重程度而明显升高,可作为CAP患者预后生存情况的预测指标。
Objective To explore the different severity community acquired pneumonia（CAP）the prognosis of patients with survival situation and the correlation of blood coagulation function. Methods A retrospective analysis of hospital respiratory between September 2011 and December 2011 treated 89 cases of adult patients with CAP as the research object, according to the skills criteria into low-risk group and high-risk groups. There are 47 people in the low-risk group and 42 people in the high-risk group. Comparison of two groups of patients with general information and the platelet count（PLT）,prothrombin time（PT）,activated part of clotting enzyme live time（APTT）,thrombin time（TT）,fibrinogen（Fib）,and D-dimer（DD） and so on blood coagulation function index,analysis of survival in patients with different prognosis group differences. Results In high risk patients with CAP of PT,TT and the DD values were（16.2±1.5） s,（16.9±1.9） s,（8.1±7.4） mg/L,and were significantly higher than that of low risk patients（11.5±1.4） s,（9.5 ±1.7）s,（1.6±3.2）mg/L,and the differences were statistically significant（P〈0.01）,the difference of the PLT,APTT,Fib has no statistical significance（P〉0.05）. Conclusion CAP can lead to blood coagulation dysfunction,in patients with blood plasma D-dimer obviously increased with the illness severity,and can be used as a predictor of survival prognosis in patients with CAP.
出处
《实用医技杂志》
2015年第7期699-700,共2页
Journal of Practical Medical Techniques
