摘要
目的：探讨标准化流程在甲氨蝶呤治疗原发性中枢神经系统淋巴瘤（PCNSL）中的应用效果。方法：选择2011年1月~2014年12月间我科收治的102例需行大剂量甲氨蝶呤化学治疗（化疗）的PCNSL患者,将其随机分为实验组和对照组,每组分别51例。实验组采用PCNSL临床诊疗护理标准化流程来指导临床;对照组则采用常规诊疗护理方法。比较两组患者化疗过程中不良反应发生率、患者满意度间的差异。结果：实验组不良反应发生率和程度低于对照组（P〈0.05）,患者满意度高于对照组（P〈0.05）。结论：PCNSL临床诊疗护理标准化流程的应用可降低患者化疗期间不良反应发生率,并提高患者满意度。
Objective： To explore the application effect of standardized process in the process of methotrexate in the treatment of primary central nervous system lymphoma（PCNSL）.Methods： From January 2011 to December 2014,102 patients with PCNSL who need high- dose methotrexate chemotherapy was randomly divided into experimental group and control group,there was 51 cases in each group.The experimental group used standardized process to guide the clinical work; while the control group received conventional treatment and nursing methods.And then compare the adverse reaction and patient satisfaction between the two groups.Results： The occurrence rate and degree of adverse reaction in the experimental group was lower than the control group（P〈0.05）,and patient satisfaction was higher than the control group（P〈0.05）.Conclusion： The application of PCNSL standardized process can reduce the occurrence rate of adverse reactions during chemotherapy and improve the patient satisfaction.Therefore,it is worth clinical popularizing.
出处
《中国医药导刊》
2015年第6期616-618,共3页
Chinese Journal of Medicinal Guide
