期刊文献+

普萘洛尔联合咪喹莫特治疗增生期婴幼儿血管瘤的临床效果

Clinical efficacy of combined propranolol and imiquimod treatment in infantile hemangioma of proliferative phase
原文传递
导出
摘要 目的评估普萘洛尔联用咪喹莫特治疗婴幼儿血管瘤的临床疗效和安全性。方法将53例增生期血管瘤患儿随机分为观察组和对照组,其中观察组34例,口服普萘洛尔并外涂咪喹莫特治疗;对照组19例,给予门诊随访观察及常规诊疗,比较两组患儿的血管瘤变化情况,并评价观察组患儿服药前后的心率、血糖、肾功能、肝功能等。结果经过6个月的治疗,有效率观察组为97.1%(33/34),对照组为57:9%(11/19),差异有统计学意义(P〈0.05);观察组治疗前后心率有变化,其他如血糖和肝功能、肾功能等差异无统计学意义(P〉0.05)。结论普萘洛尔和咪喹莫特联用对婴幼儿增生期血管瘤有明显抑制和治疗作用,可以加速血管瘤的消退,其不良反应轻微,安全性高。 Objective To observe the clinical effect and safety of propranololand imiquimod therapy for infantile hemangiomas of proliferative phase. Methods A total of 53 infantile patients with hemangiomas of proliferative phase that were treated in our department were collected. According to patient's condition, the patients were classified into treatment group and observation group. The treatment group consisted of 34 patients received propranolol and imiquimod treatment, and 19 cases belonged to the observation group. The changes of tumor were compared between the treatment group and the observation group. Pre-therapeutic and post-therapeutic heart rate, blood pressure, blood glu- cose were monitored in the treatment group, so were in post-treatment. Results After 6 months, the effective rate was 97.1~/00 (33/34) in treatment group, and the effective rate was 57.9~ (ll/19)in ob- servation group. There was significant difference between treatment group and observation group in ef- fective rate (P^0.05), and so did blood pressure and heart rate after medication in the treatment group, but not in blood glucose, heart rate six hours after medication (P^0.05). Conclusions Prop- ranolol and imiquimod therapy has a certain inhibitory effect on infantile hemangiomas of proliferative phase. Propranolol and imiquimod are safe in patients with infantile hemangioma, and adverse reactions are mild.
出处 《中华医学美学美容杂志》 2016年第2期98-101,共4页 Chinese Journal of Medical Aesthetics and Cosmetology
关键词 普萘洛尔 咪喹莫特 婴幼儿 血管瘤 Propranolol Imiquimod Infantile Hemangioma
  • 相关文献

参考文献16

二级参考文献62

共引文献115

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部