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偏头痛的遗传学研究进展 被引量:13

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摘要 偏头痛是一种常见的神经血管紊乱疾病,其发病机制还不十分清楚,遗传因素和环境因素共同作用促使其发生。偏头痛的遗传学机制目前研究还不透彻,唯一定论的是符合孟德尔遗传的家族性偏瘫型偏头痛(familial hemiplegic migraine,FHM),此外还有很多离子通道基因、神经系统相关基因、血管基因以及激素相关基因与偏头痛易感性有关,但这些候选基因是否属于偏头痛的致病基因还需要大量实验验证。表观遗传学在偏头痛发病机制中可能发挥一定的作用,其研究还处于起步阶段。
作者 刘东 万琪
出处 《中国疼痛医学杂志》 CAS CSCD 2015年第4期289-292,共4页 Chinese Journal of Pain Medicine
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