摘要
目的:观察头风汤对偏头痛(肝阳上亢夹瘀证)患者的临床效果、血清hs-CRP表达和脑动脉血流速度的影响。方法:选取符合诊断标准的80例偏头痛患者,将其随机分成治疗组和对照组。治疗组予以头风汤配方颗粒,每次一袋,每日三次,餐后冲服,对照组予以萘普生片0.2g,每日两次,饭后服用,疗程均为30天。观察两组患者治疗前后总有效率、中医证候积分、血清hs-CRP表达和脑动脉血流速度。结果:治疗后两组均效果明显,但两组总有效率差异无统计学意义(P>0.05)。中医证候均明显改善(P<0.01),且治疗组显著优于对照组(P<0.01)。两组患者血清高敏C反应蛋白(hs-CRP)水平均显著降低(P<0.01),治疗后两组患者大脑前动脉(ACA)、大脑中动脉(MCA)、大脑后动脉(PCA)、基底动脉(BA)、椎动脉(VA)的平均血流速度(Vm)均显著降低(P<0.01)。结论:头风汤能够明显改善偏头痛(肝阳上亢夹瘀证)患者的临床症状以及中医证候积分,降低患者的血清hs-CRP,能够改善脑的血流速度。
Objective:To observe the effects of Toufeng Decoction on the clinical effects,serum hs-CRP serum expression and cerebral artery blood flow velocity in patients with migraine(Syndrome of hyperactivity of liver-yang with blood stasis).Methods:Eighty migraine patients who met the inclusion criteria were randomly divided into treatment group and control group.The treatment group was given Toufeng Decoction formula granules,1 pack each time,3 times a day after meals,Control group was given naproxen tablets 0.2 g,twice a day after meals.Both groups were treated for 30 days.The total effective rate,TCM symptom score,serum hs-CRP expression and cerebral artery blood flow velocity were observed before and after treatment in both groups.Results:After treatment,the total effect was significant in both groups,but there was no significant difference in the total effective rate between the two groups(P>0.05).The TCM symptoms were all significantly improved(P<0.01),and the treatment group was significantly better than the control group(P<0.01);the serum high-sensitivity c-reactive protein(hs-CRP)levels were significantly reduced in both groups(P<0.01);the anterior cerebral artery(ACA),middle cerebral artery(MCA)and posterior cerebral artery(PCA),basilar artery(BA),vertebral artery(VA)and the average blood flow velocity(Vm)were significantly reduced in both groups after treatment(P<0.01).Conclusion:Toufeng Decoction can significantly improve the clinical symptoms and TCM syndrome scores of migraine patients(Syndrome of hyperactivity of liver-yang with blood stasis)reduce the hs-CRP serum,and improve cerebral blood flow velocity.
作者
张利
杨彩虹
ZHANG Li;YANG Caihong(Chengdu university of traditional Chinese medicine affiliated hospital shuangliu branch,Chengdu Sichuan 610200,China)
出处
《四川中医》
2023年第4期169-172,共4页
Journal of Sichuan of Traditional Chinese Medicine
基金
成都市卫健委科研课题(编号:2020036)
关键词
头风汤
偏头痛
血清HS-CRP
脑动脉血流速度
Toufeng Decoction
Migraine
The hs-CRP serum
cerebral artery blood flow velocity
