摘要
探讨小剂量地西他滨单药治疗在老年慢性粒单核细胞白血病治疗中的疗效及安全性。应用地西他滨10 mg/m24天方案治疗慢性粒单核细胞白血病,观察其疗效。2例患者在应用地西他滨后获得明显疗效,脱离输血,且未出现明显副反应。小剂量地西他滨治疗老年慢性粒单核细胞白血病疗效显著,耐受性较好。
Objective To evaluate the clinical therapeutic effect and safety of decitabinein the treatment for chronic myelomonocytic leukemia （CMML）. Methods 2 patient with CMML were treated withdecitabine at a dose of 10mg/m^2 for 4 days. Blood routine test was used to evaluate the efficacy of the treatment and adverse effect. Results Both of the two patients achieve part remission. The transfusion was improved. No severe adverse effects were observed. Conclusions Decitabine can effectively treat CMML with mild toxicities.
出处
《齐齐哈尔医学院学报》
2015年第15期2233-2234,共2页
Journal of Qiqihar Medical University
