摘要
目的:了解本院鲍曼不动杆菌(AB)临床分布及耐药性特征。方法对2012~2013年共计1190株AB临床分布特征、药敏实验结果进行回顾性分析。结果1190株AB主要分离自痰标本,主要分布于重症监护病房、神经外科和呼吸内科。AB对多数抗菌药物的耐药率达到60%~80%,其中对妥布霉素、哌拉西林/他唑巴坦和亚胺培南的耐药率上升最为显著,对头孢哌酮/舒巴坦的耐药率有所下降。结论 AB对多种抗菌药物耐药严重,且耐药性上升趋势明显。应加强耐药性监测,合理使用抗菌药物,防止耐药株的产生和流行。
Objective To study the clinical distribution and drug resistance of Acinetobacter baumannii (AB) .Methods Clinical distribution and drug resistance of 1 190 strains of AB ,isolated in 2012 and 2013 ,were retrospectively analyzed .Results Most of AB strains were isolated from sputum ,and mainly from Intensive Care Unit ,Department of Neurosurgery and Department of Re‐spiratory .Resistance rates of AB to most antimicrobial agents were 60% -80% .Resistance rate to tobramycin ,piperacillin/tazobac‐tam and imipenem was increased significantly .Resistance rate to cefoperazone/sulbactam was decreased .Conclusion Drug resist‐ance of AB might be serious ,with increasing tendency .
出处
《国际检验医学杂志》
CAS
2015年第10期1349-1350,1353,共3页
International Journal of Laboratory Medicine
基金
深圳市科技创新委员会深圳市科技计划项目(JCYJ20140414170821183)
关键词
鲍曼不动杆菌
临床分布
耐药性
抗菌药物
Acinetobacter baumannii
clinical distribution
drug resistance
antimicrobial agents