摘要
目的 探讨倍他米松新霉素软膏联合碳酸氢钠外敷对儿童轻度海蜇蜇伤的疗效.方法 将416海蜇蛰伤轻症患儿随机分为实验组208例和对照组208例,对照组采用5～10％碳酸氢钠冷湿敷,实验组在对照组基础上联合倍他米松新霉素软膏外用;比较两组患儿的临床疗效、临床症状和体征改善情况;并对两组患者治疗后外周血白细胞计数（WBC）、谷丙转氨酶（ALT）、血清肌酐（SCr）、肌酸激酶同工酶（CKMB）水平进行分析.结果 实验组总有效率为96.15％,对照组为95..19％,两组相比差异无统计学意义（x2=0.111,P＞0.05）;治疗3d后两组患者皮肤受损程度、皮肤受损面积、瘙痒症状积分相比差异无统计学意义（P＞0.05）;治疗后实验组WBC、ALT、SCr、CKMB水平虽然较对照组有所降低,但两组间相比差异无统计学意义（P＞0.05）.结论 轻度海蜇蛰伤的患儿采用5～10％碳酸氢钠冷湿敷与碳酸氢钠湿敷联合激素软膏外用疗效相当,临床上可以考虑单独采用碳酸氢钠冷湿敷,从而避免过度治疗。
Objective To explore the clinical effect of betamethasone neomycin ointment combined with external application of sodium bicarbonate on hurt by jellyfish of child. Methods 416 children with mild jellyfish stings hurt were randomly divided into experimental group （208 eases） and control group （208 cases）. Control group was treated with 5 10% sodium bicarbonate cold wet compress. The experimental group was treated based on the control group and with betamethasone neomycin ointment. The clinical efficacy, clinical symptoms and signs of improvement were observed. Blood cell count （WBC）, alanine aminotransferase （ALT）, serum creatinine （SCr） and creatine kinase isoenzyme MB （CKMB） were measured. Results The total effective rate of experimental group and control group were 96.15% and 95.19% （χ2=0. 111 ,P〉0.05）. 3D after treatment, skin damage, damage area and itching symptom score had no signif- icant difference （P〉0.05） between the two group. WBC, ALT, SCr and CKMB had no significant difference between the two group （P〉0.05）. Conclusion The efficacy of betamethasone neomycin ointment combined with external application of sodium bicarbonate and external application of sodium bicarbonate on hurt by jellyfish of child is similar.
出处
《西部医学》
2015年第5期701-703,共3页
Medical Journal of West China
基金
河北省科技支撑计划项目(132777227)
关键词
倍他米松新霉素软膏
碳酸氢钠
海蜇蜇伤
过度治疗
Betamethasone neomycin ointment
Sodium bicarbonate
Jellyfish stings
Overtreatment
