摘要
目的提供中老年实验食蟹猴的一般生理指标、血液生理生化指标的参考值。方法选取119只11~16岁食蟹猴,雄性80只,雌性39只,分别检测其一般生理指标（体重、体长和腰围）、血液学指标和血液生化学指标,并进行性别间比较。结果雌雄动物相比,一般生理指标包括体重、体长和腰围差异有显著性（P〈0.01）;血常规指标中NEUT#、LYMPH#、EO#、BASO#、NEUT%、LYMPH%、EO%、BASO%、MCV、MCH、RDW-CV、PCT、MONO%、HGB、HCT、MCHC、RDW-SD、MPV差异有显著性（P〈0.01或P〈0.05）,其余差异无显著性（P〉0.05）;血生化指标中TBIL、ALB、GLO、A/G、ALP、GLU、UREA、CREA、TCH、TG、CK、ALT、GGT差异有显著性（P〈0.01或P〈0.05）,其余差异无显著性（P〉0.05）。结论本研究提供了中老年食蟹猴一般生理指标、血液学和血液生化学的背景数据,为其在生物医学领域的应用提供参考资料。
Objective To provide reference of the general physiological index, blood physiology and biochemistry for middle and old-aged cynomolgus monkey. Methods 119 cynomolgus monkey aged from 11 -16 （80 were males and 39 were females） were involved in the study. We detected the general physiological index（body weight, the crown-rump length and waist circumference ）, hematology and blood biochemistry parameters respectively and compared these parameters between males and females. Results Between males and females, there were significant differences in Body weight, the crown-rump length and Waist circumference of the general physiological index（ P 〈 0. 01 ） , NEUT#.LYMPH#. EO#,BASO#,NEUT% ,LYMPH% ,EO% BASO% ,MCV,MCH,RDW-CV,PCT,MONO% ,HGB ,HCT,MCHC,RDW-SD~ MPV of hematology（P 〈 0. 01 or P 〈 0. 05）and TBIL,ALB,GLO,A/G,ALP,GLU,UREA,CREA,TCH,TG,CK,ALT, GGT of blood biochemistry（P 〈 0. 01 or P 〈 0. 05 ）. There were no significant differences in other parameters （P 〉 0. 05 ）. Conclusion It provides reference of general physiological index, blood physiology and biochemistry parameters of cynomolgus monkey and basis for their application in biomedical domain.
出处
《中国比较医学杂志》
北大核心
2015年第3期13-17,共5页
Chinese Journal of Comparative Medicine
基金
2012年海南省重点科技计划项目(ZDXM20120041)
关键词
食蟹猴
体重
体长
腰围
血液学
血液生化学
Cynomolgus monkey
Body weight
Crown-rump length
Waist circumference
Hematology
