摘要
目的评价大黄灌肠联合前列地尔在重症急性胰腺炎(SAP)中的作用,探求治疗SAP有效、安全、经济的方法。方法将120例SAP患者随机分为3组,对照1组40例予常规治疗,对照2组40例予常规加前列地尔治疗。治疗组40例予常规加前列地尔及大黄灌肠治疗,3组均治疗7 d后,比较治疗前后血浆D-二聚体、C反应蛋白(CRP)、Balthazar CT评分,及治疗后首次自主排便时间、腹痛缓解时间。结果 3组治疗后D-二聚体、CRP水平及Balthazar CT评分、首次自主排便时间及腹痛缓解时间两两比较差异均有统计学意义(P<0.05),且治疗组优于对照1、2组(P<0.05)。结论大黄灌肠联合前列地尔治疗SAP有效、安全,值得推广。
Objective To evaluate the efficacy and safety of Rhubarb combined with Alprostadil for severe acute panereatitis （SAP）. Methods 120 patients with SAP were randomly divided into three groups. 40 cases in treatment group were treated by Rhubarb combined with Alprostadil on the basis of routine therapy. 40 cases in con- trol group 1 were treated by routine therapy combined with Alprostadil. 40 patients in control group 2 were treated by routine therapy. The course was seven days in three groups. The changes of the creative active protein （CRP） and D - dimer before and after treatment were detected. Balthazar CT severity index, the first independent defecation time, as well as the abdominal pain relief time were observed for the evaluation of the treatment effect. Results There were significant differences between three groups on the level of D - dimer, CRP, Balthazar CT severity index, the first independent defecation time and abdominal pain relief time （ P 〈 0.05）. Conclusion Compared with the tra- ditional therapy alone, Rhubarb combined with Alprostadi therapy for SAP has a better curative effect, and is worthing of clinical reference.
出处
《河北中医》
2015年第3期376-378,共3页
Hebei Journal of Traditional Chinese Medicine
基金
河北省衡水市科学技术局2012年度衡水科学技术研究与发展计划项目(编号:12012A)
关键词
胰腺炎
大黄
前列地尔
灌肠
中西医结合疗法
Sever acute pancreatitis
Rhubarb
Alprostadi
Combined therapy of Chinese and Western Me-docome
