摘要
目的分析HIV感染者发展为AIDS患者的影响因素。方法从中国疾病预防控制信息系统艾滋病综合防治信息系统下载1995-2013年历史卡片,使用Excel建立数据库,并使用SPSSl9.0进行数据处理和统计分析。结果1995-2013年共有2187例HIV感染者发展为AIDS患者,转换率为43.71%(2187/5003),平均转变时间为(2.132±0.843年);非条件Logistic回归分析显示,有性传播疾病史(OR=1.588,P=0.003,95%C1:1.174~2.149)、注射毒品感染(OR=1.719,P=0.001,95%CI:1.593~3.871)、配偶检测HIV(+)(OR=1.393,P〈0.001,95%C1:1.176~1.650)这三个因素是HIV进展为AIDS的危险因素(OR〉1);21~30岁(OR=0.179,P=0.014,95%CI:0.045~0.706)、样本来源检测咨询(OR=0.674,P=0.037,95%CI:0465~0.977)、随访(OR=0.302,P〈0.001,95%CI:0.207,0.439)这三个因素是HIV进展为AIDS的保护因素(OR〈1)。结论有性病史、注射毒品感染和配偶HIV(+)的HIV感染者更容易发展为艾滋病患者,青壮年、咨询检测和定期随访是延缓病程发展的因素。
Objective To analyze the influencing factors of HIV infection developed into AIDS in Qujing city. Meth- ods The patient data with the address in Qujing City were collected from the Chinese Information System for Disease Control and AIDS Control and Prevention Information System. Using Excel to establish database and the SPSS 19.0 software to process and analyze data. Results Unconditional Logistic analysis results showed that: Had history of sexually transmitted diseases (STD) ( OR = 1. 588, P = 0. 003, 95% CI: 1. 174 - 2. 149), infected by injecting drug users ( OR = 1. 719, P = 0. 001,95% CI: 1. 593 - 3. 871 ), and the spouse test HIV ( + ) ( OR = 1. 393, P 〈 0. 001,95% CI: 1. 176 - 1. 650) were the risk factORs of HIV in- fection developed into AIDS ( OR 〉 1 ). However, 21 - 30 years old ( OR = 0. 179,P = 0. 014,95% CI. 0.045 - 0.706) , the sample source from testing and counseling ( OR = 0.674 P = 0.037, 95% C1:0465-0. 977), regular follow-up (OR =0. 302 ,P 〈 0. 001, 95% CI:O. 207 -0. 439) were the protection factors of HIV infection developed into AIDS ( OR 〈 1 ). Conclution Ones who had history of ( STD), infected by injecting drug users and the spouse test HIV ( + ) are more likely to develop into AIDS. The young a- dults, testing and counseling, and regular follow-up can delay disease progression.
出处
《中国皮肤性病学杂志》
CAS
CSCD
北大核心
2015年第3期271-273,282,共4页
The Chinese Journal of Dermatovenereology