摘要
目的探讨盐酸氟桂利嗪对高血压脑出血患者经颅多普勒血流参数和脑血肿体积及神经功能的影响。方法将76例高血压脑出血患者根据入院时间分为盐酸氟桂利嗪治疗组和对照组,相同时间点采用经颅多普勒诊断技术检测颅内动脉血流参数的变化,通过头颅计算机X射线断层扫描技术检测颅内血肿大小,进行神经功能评分。结果盐酸氟桂利嗪治疗组颅内动脉平均流速的下降程度明显低于对照组,神经功能评分优于对照组,但血肿体积较对照组无明显减小。结论在不扩大脑血肿情况下,盐酸氟桂利嗪能改善脑出血患者的脑部血供,有利于神经功能恢复。
Objective To explore the effect of flunarizine hydrochloride on transcranial Doppler ultrasound（TCD）observation and size of cephalophyma in acute hypertensive intracerebral hemorrhage（HICH）patients.Methods Seventy-six patients of acute HICH were randomized to the flunarizine hydrochloride-therapy group and control group.The TCD and CT were applied to monitor the blood flow parameters of intracranial arteries and the size of cephalophyma.Scoring of neurological function deficit and survival skills were used to assess overall neurological function.Results In the flunarizine hydrochloride-therapy group,the reductions of mean velocity in intracranial arteries were less than control group,the neurological function scoring was significantly better than control group（P〈0.05）,but the size of cephalophyma was not significantly reduced than control group.Conclusion Flunarizine hydrochloride can improve cerebral blood supply,and is beneficial to neurological function recovery with no enlargement in size of cephalophyma in HICH patients.
出处
《山西医药杂志》
CAS
2015年第1期12-15,共4页
Shanxi Medical Journal
关键词
颅内出血
高血压性
血流动力学
血肿
硬膜下
颅内
氟桂利嗪
超声检查
多普勒
经颅
Intracranial hemorrhage
hypertensive
Hemodynamics
Hematoma
subdural
intracranial
Flunarizine
Ultrasonography
Doppler
transcranial
