摘要
目的 动态观察高血压脑出血患者局部脑血流量变化和临床的相关性。方法 对我院 1997年 2月至 1999年 4月住院的 115例高血压脑出血患者 ,于发病 3d内首次行单光子发射计算机断层显像 (SPECT)检查 ,其中 6 7例于发病 10～ 15d行第 2次SPECT检查 ,2 5例于 2 0～ 2 5d行第 3次SPECT检查 ,图像的处理和临床评分采用盲法分析。结果 (1)在急性期 (3d内 )血肿周围存在局限性缺血 (10 0 % ) ,丘脑、内囊出血引起的远隔区域缺血最明显 (2 0 %～ 10 0 % ,10 %～ 6 9% ) ,基底节区其他部位出血次之 (7%～ 5 0 % ) ,脑叶出血最少 (3% )。血肿越大、临床表现越重 ,局部和远隔部位缺血越明显 (14%～ 81% ,19%～ 6 1% ) ;(2 )引起缺血的高峰期在 10～ 15d ,临床表现随着缺血的改善而好转。结论 SPECT对脑出血患者脑血流量变化规律的研究和临床治疗及预后的估计都有重要价值。
Objective To investigate the dynamic changes of regional cerebral blood flow (rCBF) and clinical relations in patients 3 days after the onset of hypertensive intracerebral hemorrhage Methods The dynamic SPECT on 115 patients with hypertensive intracerebral hemorrhage within 3 days after its onset from February 1997 to April 1999 was carried out in our hospital Of them, 67 patients were performend the second time in 10～15 days,and 25 were done the third time in 20～25 days after onset The images and clinical data were assessed with blind analysis Results (1) In acute stage (within 3 days after onset), there were regional ischemia in the regions around hematoma (100%) The distal ischemia was prominent in patients with hematoma in thalamus (20%～100%) and internal capsule (10%～69%), but least in cerebral lobar,rather often in regions of basal ganglia The bigger the hematoma is, the more serious the clinical manifestation, and more obvious the regional and distal ischemia (2) Ischemic peak was show on 10～15 th days The patients improved following the improvement of the ischemia Conclusions SPECT is helpful for study of changes of rCBF after the onset of hypertensive intracerebral hemorrhage The results suggested that SPECT would facilitate the therapy and prognosis for patients with hypertensive intracerebral hemorrhage
出处
《中华神经科杂志》
CAS
CSCD
2000年第5期277-279,共3页
Chinese Journal of Neurology
基金
四川省卫生科研基金!资助项目 (96 0 0 6 1)
关键词
高血压
脑出血
血流速度
临床
相关性
Hypertension
Cerebral hemorrhage
Blood flow velocity
