摘要
目的探讨慢性阻塞性肺疾病(简称慢阻肺)患病率及危险因素,提高慢阻肺早期诊断率。方法使用统一问卷对体检中心483例体检人员进行问卷调查,然后进行肺功能检测。结果慢阻肺组得分较非慢阻肺组高(P<0.01)。问卷得分与FEV1/FVC呈负相关(P<0.01)。以17分为截断点时,问卷的灵敏度、特异度、假阳性率、假阴性率、正确诊断指数、约登指数、阳性似然比、阴性似然比分别为97.3%、71.3%、28.7%、2.7%、73.3%、0.69、3.39、0.04。ROC分析曲线下面积为0.919,本人群最佳截断点为19.5分。慢阻肺总患病率为7.6%,男性患病率高于女性(P<0.01),随年龄增大慢阻肺患病率增大。性别、年龄、吸烟、BMI、学历与患慢阻肺危险性因素有关。结论慢阻肺筛查问卷可以用来初步筛查慢阻肺高危人群,结合肺功能检查可提高慢阻肺早期诊断率。
Objective To discuss the risk factors and to improve the diagnostic rate of chronic obstructive pulmonary diseases. Methods 483 people visiting the medical examination center were recruited and their data were acquired by questionnaires. Then they were given pulmonary function test. Results Compared with the non-COPD group, the scores of the questionnaires were significantly higher in the COPD group （P〈0. 01） and the scores of the questionnaires were negative correlated with FEV1/FVC. With a cut-off value of 17 points, the sensitivity, specifici-ty, mis-diagnostic rate, omission diagnostic rate, Youden′s index,positive likelihood ratio, and negative likelihood ratio were 97. 3%, 71. 3%, 28. 7%, 2. 7%, 73. 3%, 0. 69, 3. 39 and 0. 04 respectively. The area under the ROC curve was 0. 919 and the optimal cut-off point value was 19. 5. The overall prevalence rate was 7. 6% and it increased with age. The prevalence rate of male was higher than female （ P〈0. 01 ） and the risk factors were gender, age, smoking, BMI and education level. Conclusion The screening questionnaires can help preliminary screen COPD patients, and the early diagnostic rate can be improved while combined with pulmonary function test.
出处
《临床肺科杂志》
2015年第3期500-503,共4页
Journal of Clinical Pulmonary Medicine
关键词
慢性阻塞性肺疾病
筛查问卷
肺功能
早期诊断
chronic obstructive pulmonary disease screening questionnaire pulmonary function early di-agnosis
