摘要
目的 探讨硬性透气性角膜接触镜（RGPCL）在眼表面的形状稳定性及角膜形态对其的影响.方法 22名志愿者42只眼,用鹰式角膜地形图测量角膜像差后给予验配RGPCL,同样仪器测量RGPCL的像差后派发给志愿者,连续配戴1个月后回访,分别测量戴镜状态下以及摘镜30 min后的角膜地形图.采用配对t检验、W检验及相关分析对数据进行分析.结果 RGPCL戴到眼表面后,主要表现为离焦C4增加,右眼为离体（1.003 ±0.131） μm,在体（1.065 ±0.160） μm（P =0.015）;左眼为离体（1.003±0.130） μm,在体1.069（0.851,1.594）μm,（P =0.017）,水平/垂直散光C5变负,右眼为离体（0.072±0.083） μm,在体（-0.312 ±0.232）μm（P＜0.001）;左眼为离体（0.066±0.056） μm,在体（-0.349±0.242）μm（P＜ 0.001）,以及球差C12增加,右眼为离体（0.264±0.039）μm,在体（0.295±0.048） μm （P＜0.001）;左眼为离体（0.266±0.035） μm,在体0.290（0.215,0.471） μm（P ＜0.001）.角膜像差在戴镜前后发生改变的像差项有C4,C5,C7和C8等.在体RGPCL像差C4、C5、C12均与相应的戴镜前角膜像差呈正相关（右眼：r=0.557、0.596、0.581,P＜0.01,左眼：r=0.684、0.497、0.543,P＜0.01）.结论 RGPCL戴在眼表面后,镜片前表面有一定程度的变平,球差增加,并且出现趋向于角膜的散光.RGPCL的配适不宜过于平坦.
Objective To investigate the effect of corneal irregularity on on-eye rigid gas permeable（RGP） contact lenses and the corneal shape changed by RGP contact lenses.Methods Corneal topographywas taken for 42 bare eyes of 22 subjects before and 1 month after wearing of the RGP contact lens.Off-eye and on-eye wavefront aberrations of the anterior surface of the RGP contact lens were also measured by corneal topography for the same 42 eyes.Zernike aberrations of the RGP contact lens were examined and compared to those of baseline anterior corneal surface.Results For bare eyes,C4,C5,C7 and C8 were significantly different from the baseline 30 minutes after the RGP contact lens was removed.For the on-eye RGP contact lens,three mean Zernike aberrations were significantly different from those off-eye.These were defocus C4 [OD：（1.003 ±0.131） μm off-eye and （1.065 ±0.160） μm on-eye,P=0.015; OS：（1.003±0.130） μm off-eye and 1.069 （0.851,1.594） μm on-eye,P =0.017],main axis astigmatism C5 [OD：（0.072 ±0.083） μm off-eye and （-0.312 ±0.232） μm on-eye,P〈0.001; OS：（0.066±0.056） μm off-eye and （-0.349 ±0.242） μm on-eye,P 〈0.001],and spherical aberration C12 [OD：（0.264 ±0.039） μm off-eye and （0.295 ±0.048） μm on-eye,P 〈0.001 ; OS：（0.266 ±0.035） μm offeye and 0.290 （0.215,0.471） μm on-eye,P 〈 0.001].All these three Zernike aberrations of on-eye RGP contact lenses were significantly correlated to those of the baseline corneas （OD：rc4 =0.557,rc5 =0.596,rc12 =0.581,P〈0.01; OS：rc4 =0.684,rc5 =0.497,rc12 =0.543,P〈0.01）.Conclusions The results suggest that the surface shape of on-eye RGP contact lenses is not rigid,and its change depends on irregularity of the anterior corneal surface,even if the cornea itself is changed by the RGP contact lens.It is better not to fit for RGP so flatter than the average curvature of the cornea.
出处
《中华眼科杂志》
CAS
CSCD
北大核心
2015年第1期26-31,共6页
Chinese Journal of Ophthalmology
关键词
接触镜
角膜波前像差
像差测量
Contact lenses
Corneal wavefront aberration
Aberrometry
