摘要
目的:观察针刺配合口服骨力胶囊治疗膝关节骨性关节炎的临床疗效。方法:将60例膝关节骨性关节患者随机分为3组,每组20例,分别采用针刺、口服骨力胶囊、针刺配合口服骨力胶囊治疗。分别于治疗前和治疗1个疗程后,记录并比较3组患者膝关节功能评分,并于治疗1个疗程后比较3组患者的临床疗效。结果:1膝关节功能评分。治疗前3组患者膝关节功能评分比较,差异无统计学意义[(20.63±0.94)分,(20.60±1.99)分,(19.64±2.08)分,F=1.395,P=0.459)]。治疗1个疗程后3组患者膝关节功能评分比较,差异有统计学意义[(28.67±1.31)分,(32.08±0.98)分,(33.01±2.04)分,F=18.637,P=0.008)]。进一步两两比较,针刺配合口服骨力胶囊组膝关节功能评分高于针刺组和口服骨力胶囊组(P=0.002,P=0.001);针刺组与口服骨力胶囊组比较,差异无统计学意义(P=0.157)。2临床疗效。针刺组临床控制2例、显效4例、有效10例、无效4例,口服骨力胶囊组显效3例、有效8例、无效9例,针刺配合口服骨力胶囊组临床控制3例、显效5例、有效12例。针刺配合口服骨力胶囊组的临床疗效优于其他2组(R针刺配合口服骨力胶囊组=22.82,R针刺组=29.65,R口服骨力胶囊组=39.02;χ2=0.129,P=0.006)。结论:采用针刺配合口服骨力胶囊治疗膝关节骨性关节炎,可以明显改善膝关节功能,疗效优于单纯采用针刺和口服骨力胶囊治疗,值得临床推广应用。
Objective：To observe the clinical curative effects of acupuncture therapy combined with oral application of Guli Jiaonang （骨力胶囊, GLJN）for treatment of knee osteoarthritis （KOA）. Methods：Sixty patients with KOA were randomly divided into 3 groups ,20 cases in each group. The patients were treated with acupuncture therapy （acupuncture group）, oral application of GLJN （GLJN group）and acupuncture therapy combined with oral application of GLJN（ Combination group）respectively. Knee function scores were recorded and compared between the 3 groups before treatment and after one course of treatment respectively,and the clinical curative effects were evaluated and compared between the 3 groups after one course of treatment. Results：There was no statistical difterence in knee fhnction scores between the 3 groups before treatment（20.63 ＋/-0.94,20.60 ＋/- 1.99,19.64 ＋/- 2.08 points, F = 1. 395, P = 0. 459 ）. There was statistical difference in knee function scores between the 3 groups after one course of treatment （ 28.67 ＋/- 1.31,32.08 ＋/- 0.98,33.01 ＋/- 2.04 points,F = 18. 637,P = 0.008）. Further pairwise comparison showed that the knee function score of combination group was higher than t ha! of acupuncture group and GLJN group（P = 0. 002, P = 0. 001 ）. There was no statistical difference between acupuncture group and GLJN group（ P = 0. 157）. The KOA of 2 patients were controlled,4 good, 10 fair and 4 poor in acupuncture group ;3 patients got good resuh ,8 fair and 9 poor in the GLJN group ;while the KOA of 3 patients were controlled,5 good and 12 fair in combination group. The clinicat curative effect was better in combination group compared with the other 2 groups （ Rcombination group = 22.82, Racupuncture group = 29.65, RCIJN gmaup = 39.02 ; x^2= 0. 129 ,P = 0. 006）. Conclusion： The therapy of acupuncture therapy combined with oral application of GLJN can obviously improve the function of knee in patients with KOA, and it surpasses the monotherapy of acup
出处
《中医正骨》
2015年第1期20-22,26,共4页
The Journal of Traditional Chinese Orthopedics and Traumatology
关键词
骨关节炎
膝
针刺疗法
中药疗法
治疗
临床研究性
osteoarthritis, knee
acupuncture therapy
drug therapy （TCD）
therapies, investigational
