摘要
目的:评估小梁切除术对眼表泪膜功能的影响。方法:对本院收治的62例(75眼)青光眼患者行小梁切除术,统计患者术后视觉恢复情况。同时记录患者术后1d、7d、1个月与3个月的眼表泪膜功能指标。结果:术后患者眼压与前房角开放程度具有明显下降,视力有明显提升,差异有统计学意义(P<0.05)。同时,患者术后1d,术后7d与1月后,基础泪液分泌试验(SIt)与泪膜破裂时间(BUT)均较术前降低,角膜荧光染色(FL)与干眼评分较术前增加,差异有统计学意义(P<0.05)。术后3个月后,SIt,BUT与FL均恢复至术前水平,差异无统计学意义(P>0.05)。同时患者术后结膜上皮细胞鳞状化生分级增加,杯状细胞密度降低,差异有统计学意义(P<0.05)。结论:小梁切除术可影响眼表泪膜功能,造成患者泪液分泌减少,泪膜稳定性下降,出现干眼症状。因此应重视术后可能出现的与干眼有关的并发症,积极预防与治疗,以降低干眼的发生率。
Objective：To investigate the effect of trabeculectomy on tear film. Method：62 cases （ 75 eyes） of glaucoma were received trabeculectomy, the postoperative visual recovery were counted. At the same time, the index of tear film was recorded after 1 d, 7 d, 1 month and 3 months. Result： The intraocular pressure and anterior chamber angle openness had obviously drop, the eyesight had improved significantly, the difference was statistically significant （ P 〈0.05） . At the same time, the SIt and BUT of the patients had been reduced after surgery.The FL and dry eye cornea score had increased,the difference was statistically sig-nificant （ P 〈 0.05） . After 3 months of operation, SIt, BUT and FL had recovered to preoperative levels,there was no statistically significant difference （ P 〉 0.05） . And the conjunctival epithelial squamous meta-plasia and goblet cell density were reduced, the difference was statistically significant （P 〈 0.05）.Conclu-sion：Trabeculectomy could affect ocular surface appears function and result a decrease of tear secretion.The stability appears decreased,which could cause dry eye symptoms. So it＇s possible to pay attention to postoper-ative complications related to the dry eye in order to reduce the incidence of dry eye.
出处
《河北医学》
CAS
2015年第2期246-249,共4页
Hebei Medicine
基金
陕西省榆林市科技资助基金项目
(编号:201223658)
