摘要
目的了解驻京武警某部战士干眼症患病情况,探讨其发病危险因素。方法自2008-05至2010-06抽检武警某部共680例执勤战士作为研究对象,在获得知情同意后进行干眼症问卷调查及角膜荧光素染色、泪膜破裂时间(break uptime,BUT)试验、睑板腺功能检查、基础泪液分泌试验4项干眼症的客观检查,并分析其发病危险因素。结果 680例调查对象(年龄19～25岁,平均22.9岁)干眼症的患病率为9.85%,共67例。眼部不适症状中最多见的是干涩感50例(74.62%),其次为异物感36例(53.73%)及一过性视物模糊27例(40.29%),最少见的症状为眼痛3例(4.47%)。多因素条件Logistic回归分析显示以下因素是与执勤战士干眼症相关的危险因素:睑板腺功能障碍[P<0.001,B=3.414,Exp(B)=30.375],LASIK手术史[P<0.001,B=2.624,Exp(B)=13.793],长期使用滴眼液[P<0.001,B=2.619,Exp(B)=13.717],使用视频终端[P<0.001,B=2.234,Exp(B)=9.340],是否有结(角)膜炎病史与干眼症发病无相关性。结论睑板腺功能障碍、近视眼激光手术及长期使用滴眼液,是引起执勤战士干眼症发病的主要原因。
Objective To investigate the morbidity of dry eye disease in the Beijing Armed Police Forces,and to evaluate the risk factors attributable to dry eye. Methods A total of 680 outpatients and soldiers stationed near the hospital were recruited from May 2008 to June 2010. After having informed consent from the objects, questionnaires and four dry eye tests were conducted, including fluoreseein staining test, break - up time, meibomian gland function, and Schirmer 1 test. Multivariate conditional logistic regression model was used for analysis of the risk factors. Results The six hundred and eighty soldiers ranged in age from 19 to 25 years （ with a mean of 22.9 years）. Dry eye was present in 67 （9.85%） of the study subjects. On analyzing the presenting complaints, the most common complaint was dryness, found in 50（74.62% ） subjects, followed by sense of foreign body in 36（53.73% ） and transient blurred vision in 27（40.29% ）, and the most least complaint was ocular pain in 3（4.47% ）. The following factors were associated with dry eye in a multivariate conditional logistic regression analysis： meibomian gland dysfunction （P 〈 0. 001 , B 3. 414, Exp（B） 30. 375）, ahistoryof LASIK （P〈0.001, B2.624, Exp（B）13.793）, the use of eye drop（P〈0.001, B2.619, Exp（B）13.717） and video display terminal（P 〈 0. 001, B2. 234, Exp（B） 9. 340）. No con＇elation was found between dry eye sickness and history of keratitis or conjunctivitis. Conclusions Meibomian gland dysfunction, LASIK, and a history of the use of eye drop are the major causes of dry eye among the duty troops in the Armed Police Forces.
出处
《武警医学》
CAS
2011年第2期123-125,128,共4页
Medical Journal of the Chinese People's Armed Police Force
