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血小板参数与急性脑梗死发病的相关性研究 被引量:4

Study on the Correlation Between Platelet Parameters and Acute Cerebral Infarction
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摘要 目的研究急性脑梗死患者发病与血小板参数的改变之间的相关性。方法对68例急性脑梗死患者和68名健康体检者(对照组)的血小板参数进行检测,主要包括PLT(血小板计数)、IPF(未成熟血小板比率)、MPV(血小板平均体积)和PDW(血小板分布宽度),68例急性脑梗死患者按不同的发病时间分为1周组和2周组,每组34例患者,比较两亚组和对照组之间血小板参数存在的差异。结果急性脑梗死患者发病1周组与对照组比较,PLT、IPF值、MPV和PDW均存在明显差异,具有统计学意义(P<0.05)。急性脑梗死患者发病2周组与对照组比较,PDW的比较存在明显差异,具有统计学意义(P<0.05),PLT、IPF值和MPV的比较无明显差异,不具有统计学意义(P>0.05)。结论急性脑梗死患者血小板参数的改变与其病情的变化有着密切的联系,监测急性脑梗死患者血小板参数的变化,有助于急性脑梗死患者的临床治疗和预后的判断。 Objective To study the relationship between acute cerebral infarction(ACI) patients and platelet parameters changes.Methods 68 patients with acute cerebral infarction(ACI group) and 68 healthy controls(control group) were selected, and the platelet parameters including platelet count(PLT), immature platelet fraction(IPF), mean platelet volume(MPV) and platelet distribution width(PDW) were detected and compared between two groups. 68 patients with ACI were divided into 1-week onset group and 2-week onset group according to the onset time, to compare platelet parameters with control group. Results There were statistically significant differences in PLT, IPF, MPV and PDW between 1-week onset group and control group(P〈0.05). There was statistically significant difference in PDW between 2-week onset group and control group(P〈0.05), but there were no statistically significant differences in PLT, IPF and MPV(P〉0.05).Conclusions There is closely correlation between the platelet parameters changes and condition of acute cerebral infarction. Monitoring the change of platelet parameters can help to determine the clinical treatment and prognosis of patients with acute cerebral infarction.
出处 《临床医学工程》 2015年第1期67-68,共2页 Clinical Medicine & Engineering
关键词 急性脑梗死 血小板参数 相关性 Acute cerebral infarction Platelet parameters Correlation
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