摘要
从川贝母化学成分定量、药理活性和质量分析方法等方面对川贝母进行了系统的文献整理和介绍,为其进一步的开发利用提供有益参考。依据相关文献,总结川贝母中主要成分、生物活性及其分离分析方法进展。现代研究表明,川贝母中主要活性成分为生物碱类化合物,而且药理作用广泛;此外,针对上述活性成分出现较为高效、快速的分离分析方法。为严格控制川贝母质量稳定,保证临床疗效和用药安全,推进川贝母资源开发提供了有益的研究基础。
To summarize the bioactive constituents in Fritillariae Cirrhosae Bulbus and its latest isolation and analysis methods and to come to a better understanding on the species and lprocide beneficial support for its further development. Based on the related lit- eratures, the main constituets and their bioactivities and their isolation and analysis methods were summarized. Previous pharmaco- logical investigations indicated that isosteroidal alkaloids were responsible for the therapeutic effects and other various bioactivities. Additionally, there were some new isolation and analysis methods for the above bioactive constituents. In order to control quality of Fritillariae cirrhosae bulbus were analyzed in some aspect. Therefore, establishing exclusive method of quality control will have a profound influence on the reasonable application and development.
出处
《亚太传统医药》
2015年第2期41-46,共6页
Asia-Pacific Traditional Medicine
基金
国家科技重大专项"中药安全检测技术及标准平台"项目(2014ZX09304307-002)
关键词
川贝母
现代研究
质量控制
Fritillariae Cirrhosae Bulbus
Modern Research
Quality Control
