摘要
目的探讨儿科病房多药耐药菌感染的临床分布特点,并制定预防对策,以降低患儿发生医院感染的风险,促进疾病的恢复。方法选取2011年2月-2013年12月收治的1 275例患儿送检各类标本,对多药耐药菌进行分离鉴定,并进行统计分析。结果 1 275例患儿共分离出病原菌329株,其中多药耐药菌125株,占38.0%;多药耐药菌中以产ESBLs肠杆菌最多,占80.8%,其中又以大肠埃希菌、解鸟氨酸克雷伯菌为主,分别占36.0%、16.0%,其次为耐甲氧西林葡萄球菌占12.0%,耐万古霉素肠球菌占4.8%,耐氨基糖苷类肠球菌占2.4%,痰液和粪便中的多药耐药菌检出率较高,分别占64.0%、29.6%。结论儿科病房多药耐药菌检出率较高,且多分布于呼吸道和胃肠道,临床应制定可行的措施预防多药耐药菌感染。
OBJECTIVE To explore the characteristics of clinical distribution of multidrug-resistant bacteria infections in pediatric wards and formulate the prevention countermeasures so as to reduce the risk of nosocomial infections in children and promote the recovery of disease.METHODS A total of 1 275 children who were treated from Feb 2011 to Dec 2013 were enrolled in the study,the specimens were submitted,the multidrug-resistant bacteria were isolated and identified,and the statistical analysis was performed.RESULTS Totally 329 strains of pathogens have been isolated from the 1 275 children,including 125（38.0%）strains of multidrug-resistant bacteria;the ESBLs-producing Enterobacteriaceae was dominant among the multidrug-resistant bacteria,accounting for 80.8%,and the Escherichia coli and Klebsiella ornithinolytica were the predominant species,accounting for 36.0% and16.0%,respectively,followed by the methicillin-resistant Staphylococcus（12.0%）,vancomycin-resistant Enterococcus（4.8%）,and aminoglycoside-resistant Enterococcus（2.4%）.Among the multidrug-resistant bacteria,64.0% were isolated from the sputum specimens,29.6% from the stool specimens.CONCLUSION The isolation rate of the multidrug-resistant bacteria is high in the pediatric wards,and most of the strains distribute in the respiratory tract and gastrointestinal tract.It is necessary for the hospital to formulate feasible prevention measures for the multidrug-resistant bacteria infections.
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2015年第2期438-440,共3页
Chinese Journal of Nosocomiology
基金
浙江省医药卫生科技基金资助项目(2013KYB273)
关键词
多药耐药菌
儿科病房
预防对策
Multidrug-resistant bacteria
Pediatric ward
Prevention measure
