摘要
目的探讨在早产儿静脉营养中应用左卡尼汀对改善早产儿脂肪代谢,促进生长发育的临床效果。方法将90例早产患儿分为对照组及观察组,均予保暖、静脉营养等常规治疗,观察组在此基础上静脉加用左卡尼汀治疗,比较两组疗效。结果观察组在总蛋白、白蛋白、血红蛋白、体质量生长方面均优于对照组(P<0.05),且观察组在减少早产儿胃肠外营养相关性胆汁淤积(PNAC)发病率及治疗效果均较对照组明显。结论早产儿静脉营养中应用左卡尼汀对改善早产儿脂肪代谢,促进生长发育效果明显,能降低胆汁淤积症的发生,且不良反应小。
Objective To study the effect on using L‐carnitine in early intravenous nutrition of premature infants which aims to improve fat metabolism ,promote growth and development .Methods Ninety cases of premature infants were divided into the con‐trol group and observation group .All patients received conventional treatments such as keeping warm ,giving intravenous nutrition , etc .And those in the observation group received L‐carnitine beside routine care ,then compared efficacy of 2 groups .Results Total protein ,albumin ,hemoglobin ,body weight growth of the observation group are better than those of the control group（P〈0 .05） . The observation group was superior to the control group in not only reducing incidence rate of preterm children PNAC but also in improving the treatment effect .Conclusion Using L‐carnitine in early intravenous nutrition of premature infants could improve fat metabolism ,promote growth effect ,reduce the incidence rate of cholestasis with few adverse effects .
出处
《重庆医学》
CAS
北大核心
2015年第2期192-193,196,共3页
Chongqing medicine
基金
广东省佛山市卫生局2012年度研究项目(2012350)
关键词
婴儿
早产
输注
静脉内
左卡尼汀
研究
infant,premature infusions,intravenous L-carnitine research
