摘要
目的探讨对动脉硬化患者采用中西医结合治疗的临床效果。方法 68例动脉硬化患者随机分为两组,每组34例,对照组给予瑞舒伐他汀、阿司匹林治疗,观察组在此基础上加用丹蒌片治疗,6个月为1个疗程,1个疗程后观察血清胆固醇(TG)、甘油三酯(TC)、低密度脂蛋白胆固醇(LDL-C)、高密度脂蛋白胆固醇(HDL-C)、高敏C反应蛋白(hs-CRP)以及基质金属蛋白酶-9(MMP-9)水平变化。结果两组病例治疗后总有效率比较差异有统计学意义(P<0.05);观察组治疗后的血清TG、TC、LDL-C、hs-CRP、MMP-9水平均低于对照组治疗后(P<0.05),HDL-C高于对照组治疗后(P<0.05);两组病例不良反应发生率比较差异无统计学意义。结果中西医结合治疗动脉硬化能有效改善患者各项临床症状,疗效显著,且不良反应发生率较低,值得推广。
Objective To explore the clinical efficacy on arteriosclerosis treated with the integrated Chinese and western medicine in the patients. Methods Sixty- eight cases of arteriosclerosis were randomized into two groups,34 cases in each one. In the control group,rosuvastatin and aspirin were prescribed. In the observation group,on the basis of the treatment as the control group,danlou tablets were added for 6months as 1 session. After 1 session treatment,serum TG,TC,LDL- C,HDL- C,hs- CRP and MMP- 9levels were observed. Results The total effective rate was different significantly between the two groups after treatment（ P〈0. 05）. The levels of serum TG,TC,LDL- C,hs- CRP and MMP- 9 in the observation group were lower than those in the control group（ P〈0. 05） and HDL- C was higher than that in the control group after treatment（ P〈0. 05）. The difference in the adverse reaction was not significant between the two groups.Conclusion The integrated Chinese and western medicine effectively relieves every clinical symptom of arteriosclerosis,achieves the significant efficacy and lowers the incidence of adverse reaction. Hence,this therapy deserves to be promoted.
出处
《世界中西医结合杂志》
2014年第12期1315-1317,共3页
World Journal of Integrated Traditional and Western Medicine
