摘要
目的探讨比索洛尔治疗轻中度原发性高血压的临床疗效及安全性。方法轻中度高血压患者110例,随机分为观察组(55例)和对照组(55例),观察组给予比索洛尔治疗,对照组给予苯磺酸左旋氨氯地平治疗,6个月随访,对比2组有效率、治疗前后收缩压、舒张压、心率、左心功能的变化情况,及治疗后对患者血糖、血脂的影响和不良反应。结果观察组血压、心率和左心功能均显著优于对照组,差异具有统计学意义(P<0.05);治疗后2组血糖、血脂及不良反应发生率与治疗前相比无显著变化(P>0.05)。结论比索洛尔治疗原发性高血压具有较好的临床疗效,安全性高,值得临床推广应用。
Objective To investigate the curative effect and safety of bisoprolol on treating patients with essential hypertension.Methods 110 light and moderate patients with essential hypertension were randomly divided into control group（n=55,treated with acid levamlodipine）and observation group（n=55,treated with bisoprolol）.6months after treatment,the clinical efficacy,systolic blood pressure,diastolic blood pressure,heart rate,left ventricular function,glucose and lipid levels,and adverse reactions of two groups were observed and compared.Results The clinical efficacy,blood pressure,heart rate and left ventricular function of observation group were better than these of control group,which had significant difference（P0.05）;Compared with before treatment,there were no significant difference in blood glucose and lipids,adverse reactions incidence between two groups 6months after treatment.Conclusion Bisoprolol has better curative effect and higher safety,which is worthy of clinical application.
出处
《中国实用神经疾病杂志》
2014年第24期12-13,共2页
Chinese Journal of Practical Nervous Diseases
关键词
比索洛尔
原发性高血压
疗效
安全性
Bisoprolol
Essential hypertension
Curative effect
Safety
