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糖皮质激素吸入治疗喘息型慢性支气管炎的临床疗效观察

Clinical Efficacy of Inhaled Corticosteroids for the Treatment of Chronic Asthmatic Bronchitis
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摘要 目的探讨糖皮质激素吸入治疗喘息型慢性支气管炎的疗效。方法对我院2011年3月-2014年3月收治的120例喘息型慢性支气管炎患者随机分为观察组和对照组,每组60例。观察组患者采用基础疗法联合糖皮质激素吸入治疗,对照组采用基础疗法联合?2受体激动剂吸入治疗,对两组患者的疗效进行比较。结果治疗4周后,观察组患者的总有效率为95%,显著高于对照组(85%),观察组患者的FEV1/FVC、PEF和MBC均显著高于对照组,观察组患者的不良反应发生率为3.3%,显著低于对照组(11.7%),上述差异均具有统计学意义(P〈0.05)。结论采用糖皮质激素吸入治疗喘息型慢性支气管炎疗效显著,不良反应少,值得临床推广。 Objective To investigate the efficacy of inhaled corticosteroids for the treatment of chronic asthmatic bronchitis; Methods 120 cases of patients with asthmatic chronic bronchitis received in our hospital from Mar 2011 to Mar 2014 were randomly divided into observation group and control group, with 60 cases in each group.The observation group was treated with inhaled corticosteroid therapy combined with conventional therapy,and the control group was given β2 receptor agonist inhalation therapy combined with conventional therapy, the efficacies of the two groups were compared. Results The total effective rate in the observation group was 95%, significantly higher than the control group(85%) after 4 weeks of treatment; FEV1/FVC,PEF and MBC in observation group were significantly higher than the control group, the adverse reactions rate in observation group was 3.3%,significantly lower than the control group(11.7%),all these differences were statistically significant(P〈0.05). Conclusion Inhaled corticosteroids for the treatment of chronic asthmatic bronchitis had significant effect,less adverse reactions,and worthy of promotion.
作者 赖德益
出处 《中国卫生标准管理》 2014年第24期84-85,共2页 China Health Standard Management
关键词 糖皮质激素吸入 喘息型慢性支气管炎 临床疗效 Inhaled corticosteroids Asthmatic chronic bronchitis Clinical efficacy
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