摘要
临床上当患者无法经口摄食或摄入不足时需采用肠内饲管的方式对患者施以人工喂养,同时将药物从此途径直接输入肠道内。肠内饲管给药受多种因素影响,包括饲管口径、饲管位置、药物剂型、给药方法等。错误的给药可能会导致饲管堵塞、药效降低、不良反应增加、药物剂型不相容等。临床药师通过对经饲管肠内给药的影响因素进行探讨,并提出相应对策,为临床合理用药提供依据。
When oral intake is inadequate or not recommended native method of feeding, either enterally or parenterally. Once an for a prolonged period of time, patients may require an alter- enteral route is established for nutrition delivery, drug ther- apy can also be administered via this route. The combination of enteral nutrition and drug therapy brings about questions of bio- availability, compatibility, complications and interactions. Several issues must be considered with concurrent administration of oral medications and enteral formulas, particularly continuous enteral feeding, because incorrect administration methods may result in clogged feeding tubes, decreased drug effectiveness, increased adverse effects and drug-formula incompatibilities. This article provides a general overview on effect factors of medication administration via enteral feeding tubes, including drug ad- ministration techniques, considerations for drug formulation selection, common drug interactions with enteral formulas and methods to minimize tube occlusions.
出处
《中国医院药学杂志》
CAS
CSCD
北大核心
2014年第23期2066-2069,共4页
Chinese Journal of Hospital Pharmacy
关键词
肠内饲管
饲管给药
药物剂型选择
临床药师
Enteral feeding tubes
Drug administration
Alternative medication formulations
Clinical Pharmacist
