摘要
[目的]探讨脑胶质瘤患者预后影响因素,以提高胶质瘤患者术后生存率。[方法]外科手术后经病理确诊为脑胶质瘤的患者158例,查找病历和电话随访收集其资料,生存分析单因素分析使用Kaplan-Meier法计算生存率,并采用Log-rank检验;多因素分析采用Cox分析。[结果]单因素分析表明影响预后的因素有:年龄、肿瘤级别、KPS评分、术后放疗和化疗。多因素分析显示年龄、肿瘤级别、KPS评分、术后放疗和化疗是影响预后的独立因素。[结论]年龄小、级别低、KPS评分高的患者术后预后较好,术后辅助放疗或者化疗有助于改善预后。
[Purpose] To investigate the prognostic factors and to improve the survival in patients with glioma after operation. [Methods] A total of 158 patients with gliomas confirmed by pathology were collected. The clinical data was collected by scanning medical records and telephone followup.Kaplan-Meier method and Log-rank test was used in univariate analysis whereas Cox analysis was used in multivariate analysis. [Results] Univariate analysis and multivariate analysis both showed that the prognostic factors were age,pathology grade,KPS score,postoperative radiotherapy and chemotherapy. [Conclusions] Better prognosis of glioma patients are depending on lower age and pathology grade,higher KPS score,and postoperative radiotherapy and chemotherapy.
出处
《中国肿瘤》
CAS
2014年第12期1019-1023,共5页
China Cancer
关键词
胶质瘤
预后
生存率
glioma
prognosis
survival
