摘要
目的:了解我院药品不良反应/事件(adverse drug reaction/event,ADR/ADE)发生规律及特点,促进临床合理用药。方法:收集我院2013年上报的254例ADR/ADE报告,按照患者的年龄、药品种类、给药途径、药品不良反应累及系统-器官及临床表现、合并用药情况进行分类统计与分析。结果:254例ADR/ADE报告中以抗微生物药物的发生例次为首位,占37.66%;中药注射剂次之,占15.82%。静脉滴注是引发ADR/ADE的主要给药途径,占68.99%;ADR/ADE累及的主要系统-器官为皮肤系统,临床表现主要以皮疹、瘙痒为主。结论:应加强ADR相关知识的培训,提高临床医务人员对ADR/ADE监测工作的认识,增强上报意识,减少药品不良反应的发生,确保患者用药安全。
Objective：To study the regularity and the features of adverse drug reaction /events （ ADR/ADE） occurred in our hospital , to promote rational drug use in the clinic.Methods：The reports on 254 cases of ADR/ADE collected in our hospital in 2013 ,were clas-sificated and analyzed according to the age of patients , drug types, routes of administration, organs or systems involved in drug adverse reaction, clinical manifestations and combined drugs.Results： In 254 cases, 37.66% were induced by antimicrobial drugs dominated the first place and 15.82%by the Traditional Chinese Medicine Injections as the second place.Most cases were resulted from intravenous infusion which accounted for 68.99%of the total, skin and its accessories damage accounted for the highest percentage of ADR /ADE.Conclusion：To strengthen the ADR related knowledge training , improve the ability of clinical staff during ADR/ADE monitoring work and enhance the reporting awareness in order to reduce the incidence of ADR /ADE and ensure the medication safety of patients.
出处
《中国药物评价》
2014年第4期226-228,236,共4页
Chinese Journal of Drug Evaluation
关键词
药品不良反应/事件
分析
报告
用药安全
Adverse drug reactionJevent（ADR/ADE）
Analysis
Case Reports
Medication safety
