摘要
建立了高效液相色谱法测定苄达赖氨酸滴眼液中的L-赖氨酸.使用氨基柱,流动相为乙腈∶0.04 mol/L磷酸二氢钾溶液（45∶55,用氢氧化钾溶液调至pH 6.5）,检测波长200 nm.L-赖氨酸在0.2～2.5 mg/ml范围内线性关系良好,回收率为99.04％,RSD为1.28％.
An HPLC method was established for the determination of L-lysine in bendazac lysine eye drops.An amino column was used,with the mobile phase of acetonitrile ∶ 0.04 mol/L potassium dihydrogen phosphate solution （45 ∶ 55,pH 6.5,adjusted with potassium hydroxide solution）,at the detection wavelength of 200 nm.It was linear in the range of 0.2-2.5 mg/ml.The average recovery was 99.04 ％,with RSD of 1.28 ％.
出处
《中国医药工业杂志》
CAS
CSCD
北大核心
2014年第11期1061-1062,共2页
Chinese Journal of Pharmaceuticals
