摘要
目的:探讨3种不同方法对围绝经期抑郁症的治疗效果。方法:147例围绝经期抑郁症患者随机分为A、B、C3组,每组49例,A组采用激素连续序贯疗法,B组采用心理干预联合氟西汀,C组采用心理干预+氟西汀+激素连续序贯治疗。比较3组的临床疗效。结果:C组患者的治愈率和总有效率均显著高于A组和B组,差异有统计学意义(P<0.05);C组治疗后各时间点抑郁指数均显著低于A组和B组,差异有统计学意义(P<0.05)。结论:采用心理干预,氟西汀联合激素连续序贯疗法治疗围绝经期抑郁症患者疗效肯定,值得借鉴。
Objective： To explore the curative effects of three different therapies for perimenopausal depression. Methods ： A total of 147 perimenopausal women with depression were randomly divided into group A, group B and group C, 49 women in each group. The women in group A were treated with sequential hormone therapy; the women in group B were treated with psychological intervention combined with fluoxetine; the women in group C were treated with psychological intervention, fluoxetine and sequential hormone therapy. The clinical effects in the three groups were compared. Results： The cure rate and total effective rate in group C were statistically significantly higher than those in group A and group B （ P 〈 0. 05 ） . The depression indexes at various time points after treatment in group C were statistically significantly lower than those in group A and group B （ P 〈 0. 05 ） . Conclusion ： The curative effect of psychological intervention, fluoxe- tine combined with sequential hormone therapy in treatment of perimenopausal depression is significant, which is worth learning.
出处
《中国妇幼保健》
CAS
北大核心
2014年第28期4682-4683,共2页
Maternal and Child Health Care of China
关键词
围绝经期
抑郁症
氟西汀
心理干预
Perimenopausal period
Depression
Fluoxetine
Psychological intervention
