摘要
为使偏分离群体连锁图矫正方法能被广泛应用,在Microsoft Visual Studio 2010操作平台下,利用C++语言研制了Windows界面友好的DistortedMap软件包。结果显示:DistortedMap软件包具有遗传群体模拟、偏分离群体连锁图矫正和数量性状基因座定位的功能。使用该软件包可获得偏分离标记间遗传距离的无偏估计值并消除标记偏分离对QTL定位的影响。
To facilitate the widespread use of our approaches for correcting linkage groups in segregation distortion population, C＋＋ programming language under the framework of Microsoft Visual Studio 2010 platform was used to develop a new software ,named Distorted- Map. Results showed that the DistortedMap software included three modules：simulating hi-parental populations, correcting genetic distance between distorted markers, and mapping quantitative trait locus for quantitative traits. This software can unbiasedly estimate genetic distance between distorted markers and remove the effect of marker segregation distortion on mapping quantitative trait loci.
出处
《南京农业大学学报》
CAS
CSCD
北大核心
2014年第5期13-18,共6页
Journal of Nanjing Agricultural University
基金
教育部高等学校博士点基金项目(20120097110023)
教育部新世纪优秀人才支持计划项目(NCET-05-0489)
中央高校基本科研业务费创新团队项目(KYT201002)
关键词
偏分离
连锁图
QTL定位
软件包
marker segregation distortion
linkage group
quantitative trait locus mapping
software package
