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检测血清胱抑制素和β2微球蛋白对子痫前期孕妇早期肾功能损害的诊断意义 被引量:3

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摘要 目的:探讨血清胱抑制素和β2微球蛋白水平在评估子痫前期孕妇肾功能损害的临床价值。方法:随机选取104例子痫前期孕妇,根据孕妇肾小球滤过率(GFR)分为肾功能异常组(GFR<90 mL/min/1.73m2)和肾功能正常组(GFR≥90mL/min/1.73m2),另选取正常妊娠孕妇50例为对照组,比较三组血清胱抑制素和β2微球蛋白水平。结果:在104例子痫前期孕妇中,共有28例出现肾功能异常,发生率为26.92%;肾功能异常组孕妇血清胱抑制素和β2微球蛋白水平分别为(2.58±0.22)mg/L和(1.02±0.11)mg/L,均明显高于肾功能正常组和正常孕妇组,组间比较差异有统计学意义(P<0.05)。结论:血清胱抑制素和β2微球蛋白水平是反应子痫前期孕妇肾功能损害的敏感指标,可指导临床子痫孕妇病情变化情况。
作者 高红菊
出处 《牡丹江医学院学报》 2014年第4期31-33,共3页 Journal of Mudanjiang Medical University
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参考文献11

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二级引证文献8

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