摘要
[目的]观察生津玉液汤治疗阴津亏虚型干燥综合征与羟氯喹等效性。[方法]使用随机平行对照方法,将61例门诊及住院患者按随机数字表法分为两组。对照组30例羟氯喹,0.2g/次,2次/d。治疗组31例生津玉液汤(黄精、坤草、麦冬、乌梅各10g,生甘草5g,桑椹子、女贞子、菟丝子、西洋参各10g,全瓜蒌15g,蜂蜜浓缩适量,黑芝麻10g),水煎300mL,2次/d,早晚温服。连续治疗2个月为1疗程。观测临床症状、干燥评分、不良反应。治疗1疗程,判定疗效。[结果]治疗组痊愈0例,显效8例,有效17例,无效6例,总有效率80.64%。对照组痊愈0例,显效6例,有效18例,无效6例,总有效率80%。治疗组疗效与对照组无明显差异(P>0.05)。口干、眼干评分改善治疗组治疗组优于对照组(P<0.05)。[结论]生津玉液汤治疗阴津亏虚型干燥综合征可以改善口干、眼干等症状,与羟氯喹具有等效性,值得推广。
[Objective] To observe the Fluid Nectar Soup and hydroxychloroquine treatment equivalent Sjogren syndrome. [Method] Using randomized controlled methods,61 cases of outpatients and inpatients were randomly divided into two groups. A control group of 30 cases of hydroxychloroquine,0.2g/ times,2 times /d. The treatment group of 31 cases of Fluid Nectar Soup（Huang Jing,Kun grass,dwarf lilyturf,ebony 10g 5g,licorice,mulberry,glossy privet fruit,dodder,American ginseng 10g,Fructus Trichosanthis 15g,concentrating honey right amount,black sesame 10g）,water simmer in water 300mL,2 /d,morning and evening clothes. 2 months of continuous treatment of 1 courses. Observation of clinical symptomsscore,adverse reaction,drying. 1 courses of treatment,the curative effect. [Results] The treatment group cured 0 cases,effective in 8 cases,effective 17 cases,invalid 6 cases,the total efficiency of 80.64%. The control group cured 0 cases,effective in 6 cases,effective 18 cases,invalid 6 cases,the total efficiency of 80%. The efficacy of the treatment group had no significant difference with the control group（P 0.05）. Dry mouth,dry eyes were improved in treatment group the treatment group than the control group（P 0.05）. [Conclusion] The Fluid Nectar Soup in treating Sjogren syndrome can improve the patients with dry mouth,dry eye symptoms,help dry syndrome to better treatment,worthy of promotion.
出处
《实用中医内科杂志》
2014年第6期57-59,共3页
Journal of Practical Traditional Chinese Internal Medicine
关键词
干燥综合征
生津玉液汤
阴津亏虚
燥邪伤阴
滋阴润燥
羟氯喹
中医药治疗
等效性随机平行对照研究
Sjogren＇s syndrome Sheng Jin Yu Ye Tang Yin-chun deficiency Hydroxychloroquine Dry evil injured Yin Can nourish dry Treatment of TCM Bioequivalence random parallel control
