摘要
目的研究头孢克肟产品的热稳定性,提高头孢克肟产品的质量。方法通过对不同晶体粒度和晶体型态的头孢克肟产品的稳定性实验数据进行对比和汇总,确定了头孢克肟产品影响稳定性的关键因素。结果头孢克肟的晶体粒度和晶体型态直接影响着产品的热稳定性,晶体粒度大且晶体型态均匀的其热稳定性好。结论通过对头孢克肟热稳定性的研究,产品质量得到了进一步的提升。
Objective To study thermal stability of cefixime and improve the product quality. Methods Comparing the stability data of the cefixime with different crystal particle size and type, the key factors impacting on its stability were confirmed. Results The crystal particle size and type of cefixime can impact on its thermostability. The great crystal particle size and uniform type is benefit for the thermostability. Conclusion The quality of cefixime is improved by studying its thermostability.
出处
《中国抗生素杂志》
CAS
CSCD
北大核心
2014年第7期510-512,共3页
Chinese Journal of Antibiotics
关键词
头孢克肟
热稳定性
晶体粒度
Cefixime
Thermal stability
Crystal particle size
