摘要
目的比较糖尿病(DM)与非糖尿病(NDM)急性动脉粥样硬化性血栓性脑梗死患者的病例资料、临床神经缺损程度及颅内动脉狭窄发生率、分布特点。方法筛选符合条件的2017年10月-2018年5月在铜陵市立医院住院的急性动脉粥样硬化性血栓性脑梗死患者112例纳入本研究,其中DM性脑梗死患者(DM脑梗死组)43例及NDM性脑梗死患者(NDM脑梗死组)69例,收集2组患者脑血管病的危险因素、生化检查指标、入院美国国立卫生研究院卒中量表(NIHSS)评分及颅内动脉狭窄发生率、分布特点。结果 2组患者脑血管病的危险因素比较,DM脑梗死组高脂血症、冠心病的比例、血清甘油三酯水平与NDM脑梗死组比较有明显差异(P<0.05);2组患者入院临床神经缺损程度比较,DM脑梗死组入院NIHSS≤4分患者与NDM脑梗死组入院NIHSS≤4分患者有明显差异(P<0.05);2组患者颅内血管狭窄发生率比较,DM脑梗死组血管狭窄率62.79%,其中单支血管病变率20.93%、混合血管病变率30.23%;NDM脑梗死组血管狭窄率40.58%,其中单支血管病变率57.97%、混合血管病变率20.30%,2组比较均有明显差异(P均<0.05)。结论糖尿病急性动脉粥样硬化性血栓形成脑梗死患者多伴有冠心病、高脂血症病史,入院临床神经缺损程度相对轻,颅内动脉狭窄发生率高,多以混合血管病变为主。
Objective To compare basic and clinical characteristics,clinical Neurological impairment on admission,the incidence and distribution characteristics of intracranial artery stenosis in the acute thrombotic cerebral infarction patients with diabetes mellitus (DM) and non-diabetes mellitus (NDM).Methods The qualified 112 cases of acute atherosclerotic thrombotic cerebral infarction in the study were included,43 cases of acute atherosclerotic thrombotic cerebral infarction with diabetes mellitus (DM cerebral infarction group) and 69 cases of acute atherosclerotic thrombotic cerebral infarction with non-diabetes mellitus (NDM cerebral infarction group).These patients were hospitalized in department of neurology in tongling municipal hospital from October 2017 to May 2018.risk factors of cerebral infarction,biochemical examination parameters,National Institute of Health stroke scale Score(NIHSS Score),the incidence and distribution characteristics of intracranial artery stenosis were collected.Results The hyperlipidemia cases,coronary heart disease cases and serum triglycerides levels between DM cerebral infarction group and NDM cerebral infarction group were statistically significant differences (P<0.05).Compared with the clinical Neurological impairment of the two groups,the difference between the patients of NIHSS≤4 on admission with DM cerebral infarction and the patients of NIHSS≤4 on admission with NDM cerebral infarction was statistically significant (P<0.05).The incidence of intracranial vascular stenosis was compared between the two groups.The vascular stenosis rate of DM cerebral infarction group was 62.79%,of which the single vascular lesion rate was 20.93% and the mixed vascular lesion rate was 30.23%.The vascular stenosis rate of the NDM cerebral infarction group was 40.58%,of which the single vascular lesion rate was 57.97% and the mixed vascular lesion rate was 20.30%.The difference between the two groups was statistically significant (P<0.05).Conclusion Acute atherosclerotic thrombotic cerebral infa
作者
李小元
许啟伍
朱荣志
丁凡
Li Xiaoyuan;Xu Qiwu;Zhu Rongzhi(Department of Neurology, Tongling Municipal Hospital,Tongling 244000)
出处
《卒中与神经疾病》
2018年第6期653-656,共4页
Stroke and Nervous Diseases
