摘要
近期,运用CRISPR基因编辑技术修饰人类胚胎基因,以及基因编辑婴儿事件的出现,引发了学术界以及整个社会对基因编辑技术应用以及伦理问题的争议。本文从CRISPR技术的原理,及其在医学上的应用等各方面简述了基因编辑技术的发展现状及存在的问题。同时,通过分析基因编辑婴儿事件,反思了此项技术应用产生的伦理争议及其可能产生的后果,并提供了解决伦理问题的几点对策。
Recently,a report of the world’s first gene-edited babies shocked the global scientific community and the public.Here we review the discovery and progress of CRISPR-Cas9 gene editing technology and its application in medical research.More importantly,we discuss the effect of gene editing in human embryos and the important ethical issues behind this controversy.
作者
崔建洲
林秀金
沈汉明
CUI Jianzhou;LIM Lina H. K.;SHEN Hanming(National University of Singapore,Yong Loo Lin School of Medicine Engineering,Singapore 117456,Singapore;National University of Singapore Life Sciences Institute Engineering,Singapore 117456,Singapore;National University of Singapore Graduate School for Integrative Sciences and Engineering,Singapore 117456,Singapore)
出处
《中国现代应用药学》
CAS
CSCD
北大核心
2018年第12期1755-1760,共6页
Chinese Journal of Modern Applied Pharmacy
