摘要
采用递增负荷力竭运动方式观察急性运动对肌浆网 (SR)钙转运能力的影响 ,发现运动后股四头肌SRCa2 + -ATPase活性和Ca2 + 摄取速率均明显下降 ,表现为SRCa2 + -ATPase活性和Ca2 + 摄取速率分别下降5 1.12 % (P <0 .0 1)和 17.72 % (P <0 .0 1) ;而脂质过氧化物浓度则显著升高 ,增加 4 8.85 % (P <0 .0 1)。提示急性运动后SRCa2 + -ATPase 活性和Ca2 + 摄取速率下降可能是脂质过氧化增高的结果 ,而Ca2 + 摄取功能下降可能与运动性疲劳密切相关。
Sarcoplasmic reticulum plays an important role in regulating the contraction-relaxation of skeletal muscles.This paper studied the effects of acute exercise on SR Ca transport capacity of skeletal muscles of rats. It was found that the SR Ca 2+-ATP ase activity(51.12%P<0.01) and Ca 2+ uptake rate(17.72%P<0.01) were decreased significantly after exhausted running;but the content of lipid peroxide in sarcoplasmic reticulum from the exercise group rats was significantly higher than that from the controlled rats(48.85% P<0.01). The results suggested that the enhancement of lipid peroxidation via the exercise animals might be responsible for the decreases of Ca 2+-ATP ase activity and Ca 2+ uptake rate in sarcoplasmic reticulum in the exercise animals,the reduction of SR Ca 2+ uptake rate might be closely related to exercise-induced skeletal muscle fatigue.
出处
《湘潭师范学院学报（自然科学版）》
2001年第4期38-41,共4页
Journal of Xiangtan Normal University (Natural Science Edition)
