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丹芍汤对肝肾阴虚湿热型慢性肾炎血清TNF水平的影响 被引量:4

Influence of Danshao Decoction on Serum TNF in Patients with Liver-kidney Yin Deficiency and Dampness-heat Syndrome of Chromc Nephritis
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摘要 通过放射免疫分析方法 ,检测了 30例肝肾阴虚湿热型慢性肾炎治疗前后血清TNF(肿瘤坏死因子 )含量 ,旨在探讨慢性肾炎患者血清TNF及中药丹芍汤对其影响。结果 :肝肾阴虚湿热型慢性肾炎患者血清TNF水平明显高于正常对照组 (P <0 .0 0 1 )。治疗后TNF水平明显降低 (P <0 .0 0 1 ) ,尿畸形红细胞明显减少 (P <0 .0 5 ) ,尿蛋白明显下降 (P <0 .0 0 1 )。表明TNF在慢性肾炎疾病发病中有重要意义 ,丹芍汤是治疗肝肾阴虚湿热型慢性肾炎的有效方剂。 Using radioimmunoassay,we assayed the content of serum TNF in 30 cases of chronic nephritis with liver-kidney Yin deficiency and dampness-heat syndrome before and after treatment with Danshao Decoction.The study is to probe the serum TNF level and the influence of the Decoction on it.Results:The content of TNF in experimental group patient was significantly higher than that in normal controlled group(P<0.001)?After treatment,the content of TNF got lower(P<0.001);the number of deformed RBC in urine reduced(P<0.05);the level of urinary protein decreased(P<0.05).The result showed that TNF has an important significance in pathogenesis of chronic nephritis,and Danshao Decoction is an effective prescription for liver-kidney Yin deficiency and dampness-heat syndrome of chronic ne;hritis.
出处 《辽宁中医学院学报》 2001年第4期246-247,共2页 Journal of Liaoning College of Traditional Chinese Medicine
关键词 丹芍汤 药理学 肾小球肾炎 中医药疗法 肿瘤坏死因子 肝肾阴虚湿热型慢性肾炎 Danshao Decoction pharmacology glomerulonephritis TCM treatment TNF
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