摘要
目的:观察苦芪方治疗糖尿病肾病疗效及对血糖血脂的影响。方法:将60例患者随机分为2组。治疗组35例,以苦芪方(处方:黄芪、山药、益母草、苦瓜干、玄参、番石榴、牛蒡子、天花粉、甘草)治疗;对照组25例,以科素亚治疗。2组疗程均为3月。结果:总有效率治疗组为80．0％,对照组为64．0％,2组比较,差异有显著性意义(P<0．05)。治疗后治疗组各期24h尿蛋白定量、尿白蛋白排泄率(UAER)、餐后2小时血糖(P2BG)、血清胆固醇(TC)、高密度脂蛋白-胆固醇(HDL-C)、低密度脂蛋白-胆固醇(LDL-C)、血压等指标均有明显改善,与治疗前比较,差异均有显著性意义(P<0．05)。治疗后对照组仅 UAER及血压有所变化,与治疗前比较,差异均有显著性意义(P<0．05)。结论:苦芪方治疗糖尿病肾病有较好的临床疗效,并具有减少24h尿蛋白定量、降低尿自蛋白排泄率及改善餐后血糖和脂质代谢等作用。
Objective： To observe the curative effect of Kuqi Fang （KF） for diabetic nephrosis （DN） and its influence on blood glucose and blood lipid. Methods： 60 cases were allocated to 2 groups randomly. The treatment group （35 cases）was treated by KF（composed of Radix Astragali, Rhizoma Dioscoreae, Herba Leonuri, Fructus Momordicae Charantiae （dried）, Radix Scrophulariae, Fructus Psdsidii Guajavae, Fructus Aretii, Radix Trichosanthis and Radix Glycyrrhizae）, the control group （25 cases） by cozaar. Three months constituted a course of treatment. Resuits： The total effective rate was 80.0% and 64. 0% in treatment group and control group respectively （ P 〈 0. 05）. After treatment, the 24h quantitative urinary protein, urinary albumin excretion rate （UAER）, blood glucose 2h after meal, serum cholesterol, HDL- C, LDL - C and blood pressure （BP） were markedly improved, the difference was significant as compared with before treatment （P 〈 0. 05）. After Treatment, the UAER and BP in control group was changed and the difference was significant as compared with before treatment （P 〈 0. 05）. Conclusion： KF is effective for DN and can decrease 24h quantitative urinary protein, UAER and improve the blood glucose after meal and metabolism of lipid.
出处
《新中医》
CAS
北大核心
2006年第2期36-38,共3页
New Chinese Medicine
关键词
糖尿病肾病
苦芪方
尿蛋白
血糖
高密度脂蛋白胆固醇
低密度脂蛋白胆固醇
diabetic nephrosis
Kuqi Fang
urinary protein
blood glucose
lipoproteins, high density lipoprotein-cholesterol
lipoproteins
low density lipoprotein - cholesterol
