摘要
目的观察复方牛蒡子合剂 (牛蒡子与黄芪醇提取物 )治疗糖尿病患者的临床疗效。方法分别用复方牛蒡子合剂 (治疗组 31例 )和科素亚 (对照组 2 3例 )治疗糖尿病肾病患者 ,疗程均为 3个月 ,并比较两组治疗前后的临床症状、血糖水平、脂质代谢、尿蛋白等 ,观察复方牛蒡子合剂的治疗效果。结果总有效率治疗组为 80 6 % ,对照组为 6 5 2 %。治疗组治疗后在临床症状、尿蛋白、尿白蛋白和脂质代谢等方面均较治疗前有明显改善 (P <0 0 5 ) ;对照组仅尿白蛋白一项治疗后有改善 (P <0 0 5 ) ,其余指标治疗前后比较差异无显著性。结论复方牛蒡子合剂具有减少 2 4h尿蛋白、尿白蛋白。
ObjectiveTo observe the effect of Compound Fructus Arctii Mixture (FAM, consisted of Fructus Arctii and ethanol extract of Radix Astragalus membranaceus) in treating diabetic nephropathy. MethodsUsing FAM to treat 31 patients with diabetic nephropathy and controlled by 23 patients treated with Losartan, the therapeutic course was 3 months for both groups, changes of clinical symptoms, blood glucose, lipid metabolism and urinary albumin were observed and compared. ResultsThe total effective rate in the treated group was 80 6% while in the control group 65 2%. The symptoms, urinary protein and albumin as well as lipid metabolism in the treated group all significantly improved after treatment (P<0 05), but in the control group improvement only showed in urinary albumin level (P<0 05). ConclusionFAM has the effects of reducing urinary protein in 24 hrs, lowering urinary albumin, improving blood glucose after meal and lipid metabolism.
出处
《中国中西医结合杂志》
CAS
CSCD
北大核心
2004年第7期589-592,共4页
Chinese Journal of Integrated Traditional and Western Medicine
基金
上海市科学技术发展基金资助 (No .990 4 7)
