摘要
目的 :总结微电极导向多靶点毁损手术治疗帕金森病的初步经验。 方法 :应用微电极导向技术对 2 4例临床表现为混合型的帕金森病患者进行了多靶点毁损手术治疗 ,在术毕、术后 1周进行临床疗效观察 ,统一帕金森病评定量表 ( UPDRS)综合评分对比 ,并跟踪随访 1～ 1 7个月。 结果 :全部患者肢体活动灵活性、震颤在术毕即得到显著改善 ;随访 1～ 1 7个月后症状维持稳定 ;术前和术后 UPDRS评分显著提高。 结论 :微电极导向多靶点毁损手术治疗帕金森病是切实可行的方法。
Objective: : To summarize th e preliminary experience in microelectrode-guided multi-targets lesion sterota ctic surgery for advanced Parkinson's disease. Methods: The hea ling effects of 24 patients with rigidity and tremor in unilateral and/or bilate ral extremities were observed and evaluated according to the Unified Parkinson's Disease Rating Scale (UPDRS) one week before and after microelectrode-guid ed sterotactic surgery of multi-targets lesion. Follow-up ranged from 1 to 17 months.Results: Following surgery,rigidity tremor and poor reci procal movements were significantly improved. The patients obtained good results during 1-17 months follow-up after surgery. Preoperative and postoperative UP DRS score improved significantly. Conclusion: Microelectrode-g uided sterotactic surgery of multi-targets lesion is safe and feasible for adva nced Parkinson's disease.
出处
《第二军医大学学报》
CAS
CSCD
北大核心
2001年第8期758-759,共2页
Academic Journal of Second Military Medical University
关键词
微电极导向
帕金森病
多靶点毁损术
microelectrode
Parkinson's disease
multi-targets lesi on
